Hi Henry,

You could try keeping selected atoms in the plane by manually editing
restraints in the CIF. Set _chem_comp_plane_atom.dist_esd to something
low. E.g.

loop_
_chem_comp_plane_atom.comp_id
_chem_comp_plane_atom.plane_id
_chem_comp_plane_atom.atom_id
_chem_comp_plane_atom.dist_esd
 NAG-b-D  plan1     N2        0.010
 NAG-b-D  plan1     C7        0.010
 NAG-b-D  plan1     O7        0.010
 NAG-b-D  plan1     C8        0.010
 NAG-b-D  plan2     C1        0.010
 NAG-b-D  plan2     C2        0.010
 NAG-b-D  plan2     C4        0.010
 NAG-b-D  plan2     C5        0.010

I would also check
https://mmcif.wwpdb.org/dictionaries/mmcif_pdbx_v40.dic/Items/_chem_comp_plane_atom.dist_esd.html
and try Grade2 https://grade.globalphasing.org/cgi-bin/grade2_server.cgi

Best wishes,
Tomas

On Mon, Jun 12, 2023 at 11:06 AM Henry Padley
<[email protected]> wrote:
>
> Hi all,
>
>
> I'm trying to generate a CIF file of an iridium piano stool complex ligand 
> (Cp*Ir-Phenanthroline).
>
> Can Phenix eLBOW generate correctly restrained aromatic ring systems which 
> stay flat in refinement?
>
> The phenanthroline bonds in the output CIF are listed as "aromatic" in the 
> REEL text table but they are not recognised as such in refinement. I've tried 
> manually editing the CIF via this text table to produce the alternating 
> "double/single bond" structure but it still puckers slightly in refinement.
>
> My eLBOW input is a PDB file of the ligand (I have also tried SDF input). I 
> have tried Automatic and eLBOW AM1 QM settings. Might a different Geometry 
> optimisation software selectable within eLBOW  generate the restrained 
> phenanthroline?
>
> Any advice greatly appreciated.
>
>
> Henry Padley, MSci
> School of Pharmacy
> University of Nottingham
>
>
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