Many thanks to all for your time and suggestions.

Also, my apologies - I was not aware of the phenixbb.

Best wishes,
Henry
________________________________
From: CCP4 bulletin board <[email protected]> on behalf of Nigel Moriarty 
<[email protected]>
Sent: 12 June 2023 17:26
To: [email protected] <[email protected]>
Subject: Re: [ccp4bb] eLBOW aromatic restraints

Henry

There is a PhenixBB that is more relevant to eLBOW questions but if you send me 
(directly) the inputs you used and tried, I can help you.

Cheers

Nigel

---
Nigel W. Moriarty
Building 33R0349, Molecular Biophysics and Integrated Bioimaging
Lawrence Berkeley National Laboratory
Berkeley, CA 94720-8235
Email : [email protected]
Web  : CCI.LBL.gov<http://CCI.LBL.gov>
ORCID : orcid.org/0000-0001-8857-9464<https://orcid.org/0000-0001-8857-9464>


On Mon, Jun 12, 2023 at 3:06 AM Henry Padley 
<[email protected]<mailto:[email protected]>>
 wrote:
Hi all,


I'm trying to generate a CIF file of an iridium piano stool complex ligand 
(Cp*Ir-Phenanthroline).

Can Phenix eLBOW generate correctly restrained aromatic ring systems which stay 
flat in refinement?

The phenanthroline bonds in the output CIF are listed as "aromatic" in the REEL 
text table but they are not recognised as such in refinement. I've tried 
manually editing the CIF via this text table to produce the alternating 
"double/single bond" structure but it still puckers slightly in refinement.

My eLBOW input is a PDB file of the ligand (I have also tried SDF input). I 
have tried Automatic and eLBOW AM1 QM settings. Might a different Geometry 
optimisation software selectable within eLBOW  generate the restrained 
phenanthroline?

Any advice greatly appreciated.


Henry Padley, MSci
School of Pharmacy
University of Nottingham


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