Hi Roberto,
Thanks for the link to the DeepMind site!  I hadn't seen that and now I
read it and the paper that they link to.  It looks to me as though they are
making significant progress on ligands, dna, rna, but that the program is
not yet available, so I don't think it can be tested yet!
All the best,
Tom T


On Fri, Dec 1, 2023 at 5:19 AM Roberto Steiner <[email protected]>
wrote:

> Great paper indeed!
>
> However quite significant progress seems to have been achieved with
> ligands as well (and not only)…
>
> https://deepmind.google/discover/blog/a-glimpse-of-the-next-generation-of-alphafold/
> Has anyone in the community put this to the test?
>
>
> Best wishes
> Roberto
>
>
> *Roberto A Steiner*
> www.steinerlab.org
> https://twitter.com/steiner_lab
>
> [email protected]
> Randall Centre for Cell and Molecular Biophysics
> Faculty of Life Sciences and Medicine
> King's College London
> Room 3.10A
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> SE1 1UL, London, UK
> Phone 0044 20 78488216
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>
> [email protected]
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>
> *Responses to emails are not expected outside of your normal working
> hours.*
>
>
>
>
>
>
>
>
> On 30 Nov 2023, at 22:35, Tom Terwilliger <
> [email protected]> wrote:
>
> You don't often get email from
> [email protected]. Learn why this is important
> <https://aka.ms/LearnAboutSenderIdentification>
> Hi Structural biologist colleagues!
>
> Our article that helps you make the case that the experiment is still very
> much needed is now out:
>
> https://www.nature.com/articles/s41592-023-02087-4
>
> "AlphaFold predictions are valuable hypotheses and accelerate but do not
> replace experimental structure determination."  Nature Methods (2023)
>
> Also, here is a video on the Phenix Tutorials YouTube channel that
> describes this analysis:  https://www.youtube.com/watch?v=ugMPYdPo8Bc
>
> (I hope you will be happy to see that you and your structural biology
> colleagues get the credit for making AlphaFold possible at 2:35 in the
> introduction of this video!  Keep up the fantastic structural biology work!)
>
> All the best,
> Tom T
> --
> Thomas C Terwilliger
> Laboratory Fellow, Los Alamos National Laboratory
> Senior Scientist, New Mexico Consortium
> 100 Entrada Dr, Los Alamos, NM 87544
> Email: [email protected]
> Tel: 505-431-0010
>
>
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-- 
Thomas C Terwilliger
Laboratory Fellow, Los Alamos National Laboratory
Senior Scientist, New Mexico Consortium
100 Entrada Dr, Los Alamos, NM 87544
Email: [email protected]
Tel: 505-431-0010

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