Very very interesting analysis - Thankyou! On Fri, 1 Dec 2023 at 18:01, Tom Terwilliger < [email protected]> wrote:
> Hi Roberto, > Thanks for the link to the DeepMind site! I hadn't seen that and now I > read it and the paper that they link to. It looks to me as though they are > making significant progress on ligands, dna, rna, but that the program is > not yet available, so I don't think it can be tested yet! > All the best, > Tom T > > > On Fri, Dec 1, 2023 at 5:19 AM Roberto Steiner <[email protected]> > wrote: > >> Great paper indeed! >> >> However quite significant progress seems to have been achieved with >> ligands as well (and not only)… >> >> https://deepmind.google/discover/blog/a-glimpse-of-the-next-generation-of-alphafold/ >> Has anyone in the community put this to the test? >> >> >> Best wishes >> Roberto >> >> >> *Roberto A Steiner* >> www.steinerlab.org >> https://twitter.com/steiner_lab >> >> [email protected] >> Randall Centre for Cell and Molecular Biophysics >> Faculty of Life Sciences and Medicine >> King's College London >> Room 3.10A >> New Hunt's House, Guy's Campus >> SE1 1UL, London, UK >> Phone 0044 20 78488216 >> Fax 0044 20 78486435 >> >> [email protected] >> Dipartimento di Scienze Biomediche >> Università degli Studi di Padova >> <https://www.google.com/maps/search/Padova+%0D%0AViale+G.+Colombo+3?entry=gmail&source=g> >> Viale G. Colombo 3 >> <https://www.google.com/maps/search/Padova+%0D%0AViale+G.+Colombo+3?entry=gmail&source=g> >> 35131 Padova, Italia >> Telefono 0039 049 8276409 >> >> *Responses to emails are not expected outside of your normal working >> hours.* >> >> >> >> >> >> >> >> >> On 30 Nov 2023, at 22:35, Tom Terwilliger < >> [email protected]> wrote: >> >> You don't often get email from >> [email protected]. Learn why this is >> important <https://aka.ms/LearnAboutSenderIdentification> >> Hi Structural biologist colleagues! >> >> Our article that helps you make the case that the experiment is still >> very much needed is now out: >> >> https://www.nature.com/articles/s41592-023-02087-4 >> >> "AlphaFold predictions are valuable hypotheses and accelerate but do not >> replace experimental structure determination." Nature Methods (2023) >> >> Also, here is a video on the Phenix Tutorials YouTube channel that >> describes this analysis: https://www.youtube.com/watch?v=ugMPYdPo8Bc >> >> (I hope you will be happy to see that you and your structural biology >> colleagues get the credit for making AlphaFold possible at 2:35 in the >> introduction of this video! Keep up the fantastic structural biology work!) >> >> All the best, >> Tom T >> -- >> Thomas C Terwilliger >> Laboratory Fellow, Los Alamos National Laboratory >> Senior Scientist, New Mexico Consortium >> 100 Entrada Dr, Los Alamos, NM 87544 >> <https://www.google.com/maps/search/100+Entrada+Dr,+Los+Alamos,+NM+87544?entry=gmail&source=g> >> Email: [email protected] >> Tel: 505-431-0010 >> >> >> ------------------------------ >> >> To unsubscribe from the CCP4BB list, click the following link: >> https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 >> >> >> > > -- > Thomas C Terwilliger > Laboratory Fellow, Los Alamos National Laboratory > Senior Scientist, New Mexico Consortium > 100 Entrada Dr, Los Alamos, NM 87544 > <https://www.google.com/maps/search/100+Entrada+Dr,+Los+Alamos,+NM+87544?entry=gmail&source=g> > Email: [email protected] > Tel: 505-431-0010 > > > ------------------------------ > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 > ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
