Dear colleagues, We have a new opening for a Principal Scientist, Scientific Data Processing Lead, based at GSK in Stevenage, UK.
Full details at https://jobs.gsk.com/en-gb/jobs?keywords=420441&lang=en-gb&sortBy=relevance&page=1 Closing Date for Applications 16th May 2025 For informal enquiries please contact paul.2.rowl...@gsk.com or chun-wa.h.ch...@gsk.com Thanks for your interest, Paul Rowland The UK Structural & Biophysical Sciences Centre of Excellence at Stevenage is a global multi-disciplinary department within GSK R&D that provides molecular insights into drug discovery for small molecule, oligonucleotide, biopharmaceutical and vaccine programmes. Our new CryoEM lab has state of the art facilities including two Glacios microscopes and a well-equipped sample preparation laboratory. We also have regular access to two Krios microscopes from our membership of the Cambridge CryoEM Consortium. To facilitate the rapid processing and subsequent interpretation of a continuous flow of CryoEM datasets we have embarked on building a new computing and software infrastructure from the ground up, including both on premises and in Cloud computing systems at scale. We are looking for an exceptional Principal Scientist with an interest in building and improving data processing workflows and using them to accelerate the impact of our new world class structural biology facilities. This role provides opportunities to integrate advances in prediction, modelling and AI/ML by collaborating with departments at GSK, enhancing the speed and success of drug discovery. The initial focus will be on CryoEM data processing with the expectation that it would later expand to include additional structural biology and biophysical techniques. Whilst drawing on the ideas and experience of the wider group, you will bring your own ideas to the design and implementation of the data processing workflows, building capabilities by scripting the functionalities of current CryoEM software packages. Working with live project data you will contribute to the delivery of results for drug discovery project goals, enabling the group to drive science forward. This role could be an ideal opportunity to progress your career. Whether you are interested in being an individual contributor or have leadership aspirations we would like to hear from you. Basic Qualifications & Skills: We are looking for professionals with these required skills to achieve our goals: * Advanced degree (PhD or equivalent) in a relevant scientific discipline. * Proficient programming skills, including Python and bash scripting, with experience in integrating and linking scientific software applications, especially on high-performance computing systems. * Keen interest in scientific issues, with excellent problem-solving skills. Able to identify and tackle the root cause of problems to achieve optimal solutions. * Proven ability to define strategy and actionable plans, and execute with excellence, either independently or through effective coordination with others to achieve goals successfully. * Demonstrated track record of effectively working within and across teams in matrix organizations, driving and contributing to workflows and data flows across line boundaries. * Excellent organisational, interpersonal, communication, and teamwork skills, with a strong dedication to supporting team members in achieving scientific goals and meeting deadlines. Preferred Qualifications & Skills: Please note the following skills are not necessary, just preferred, if you do not have them, please still apply: * Experience in writing data processing software pipelines for techniques such as CryoEM, X-ray crystallography, materials science, NMR, and image processing. * Detailed understanding of current CryoEM data processing software such as Relion, CryoSPARC, CCP4, CCP-EM, Doppio, and CryoCloud. * Experience with modern software development tools and practices, including object-oriented programming, Git/GitHub, DevOps tools, AI tools, Slurm, and Google Cloud. * Web development, including browser-based visualisation and plug-ins. * Proven expertise in leading the analysis and interpretation of scientific data. [cid:image001.png@01DBB7AB.55332F30] Paul Rowland Scientific Leader Protein, Cellular & Structural Sciences Target Discovery GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK paul.2.rowl...@gsk.com<mailto:xxxxxxxx.x.xxxx...@gsk.com> [cid:image002.png@01DBB7AB.55332F30]<https://www.gsk.com/> [cid:image003.png@01DBB7AB.55332F30]<https://www.facebook.com/GSK> [cid:image004.png@01DBB7AB.55332F30]<https://twitter.com/GSK> [cid:image005.png@01DBB7AB.55332F30]<https://www.linkedin.com/company/glaxosmithkline> [cid:image006.png@01DBB7AB.55332F30] GSK monitors email communications sent to and from GSK in order to protect GSK, our employees, customers, suppliers and business partners, from cyber threats and loss of GSK Information. 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