You are cordially invited to join the Center for Biomolecular Structure Lecture Series ………..
Ricardo Padua Howard Hughes Medical Institute The Scripps Research Institute WEDNESDAY, July 22, 13:30 (EDT) "Visualizing enzyme catalysis through X-ray crystallography" Register in advance for this meeting: https://bnl.zoomgov.com/meeting/register/sQhXauTtSGa3iwB6X-tQ3g Time conversion Link: https://www.worldtimebuddy.com/<https://urldefense.com/v3/__https:/gcc02.safelinks.protection.outlook.com/?url=https*3A*2F*2Fwww.worldtimebuddy.com*2F&data=05*7C01*7Cgenoa.blankenship*40pnnl.gov*7C67ffe754733240e42d3e08da641ba4bc*7Cd6faa5f90ae240338c0130048a38deeb*7C0*7C0*7C637932367171794987*7CUnknown*7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0*3D*7C3000*7C*7C*7C&sdata=aSe2IUSomjge9ZW6zXdQ81fPzxpg8eawtRkoiOEJdXM*3D&reserved=0__;JSUlJSUlJSUlJSUlJSUlJSUlJSU!!P4SdNyxKAPE!Fd5kIAbibocFpkUaEbpqZZGm8tw-xiqb5oC4sfOklv6Kbbf-T3RvUobMSLrzyXNbfNVT9vMxJGuY1RsSqbc6MjpIABre1Q$> Abstract: Understanding how protein motions contribute to enzyme function remains a central challenge in molecular biology. How are motions occurring on different timescales connected, and how do they contribute to catalytic efficiency? Have proteins evolved to preferentially access the conformational substates required for function? Recent advances in structural biology, protein engineering, and X-ray crystallography are providing new insights into these questions. Studies of directed evolution have revealed how enzyme dynamics can be optimized to produce highly efficient artificial catalysts, while developments in crystallographic data collection have enabled visualization of the molecular mechanisms underlying temperature adaptation in exceptionally proficient enzymes. Together, these findings highlight the intimate relationship between protein motions, evolution, and enzymatic function. =================================== Vivian Stojanoff, PhD Education, Training, Outreach User Program p 1(631) 344 8375 e [email protected]<mailto:[email protected]> w https://www.bnl.gov/ps/lifesciences/<https://www.bnl.gov/ps/lsbr/> Address: Center for Biomolecular Structure National Synchrotron Light Source II Building 745 Brookhaven National Laboratory Upton NY 11973 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
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BEGIN:VCALENDAR PRODID:-//zoom.us//iCalendar Event//EN VERSION:2.0 CALSCALE:GREGORIAN METHOD:PUBLISH CLASS:PUBLIC BEGIN:VTIMEZONE TZID:America/New_York LAST-MODIFIED:20260306T231828Z TZURL:https://www.tzurl.org/zoneinfo-outlook/America/New_York X-LIC-LOCATION:America/New_York BEGIN:DAYLIGHT TZNAME:EDT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 DTSTART:19700308T020000 RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=2SU END:DAYLIGHT BEGIN:STANDARD TZNAME:EST TZOFFSETFROM:-0400 TZOFFSETTO:-0500 DTSTART:19701101T020000 RRULE:FREQ=YEARLY;BYMONTH=11;BYDAY=1SU END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTAMP:20260714T135147Z DTSTART;TZID=America/New_York:20260722T133000 DTEND;TZID=America/New_York:20260722T143000 SUMMARY:CBMS Lecture Series - Padua UID:20260714T135148Z-1658275045@web-prod-gov-west1-main-6c59765b8f-s8g57 TZID:America/New_York DESCRIPTION:Vivian Stojanoff is inviting you to a scheduled ZoomGov meeti ng.\nJoin ZoomGov Meeting\nhttps://bnl.zoomgov.com/j/1658275045?pwd=l7gm WmQBCBYz5kw5RYHSsbqqvTn7A0.1\n\nMeeting ID: 165 827 5045\nPasscode: 9053 04\n\n---\n\nOne tap mobile\n+16692545252\,\,1658275045#\,\,\,\,*905304# US (San Jose)\n+16469641167\,\,1658275045#\,\,\,\,*905304# US (US Spani sh Line)\n\n---\n\nDial by your location\n⢠+1 669 254 5252 US (San Jose )\n⢠+1 646 964 1167 US (US Spanish Line)\n⢠+1 646 828 7666 US (New Yor k)\n⢠+1 669 216 1590 US (San Jose)\n⢠+1 415 449 4000 US (US Spanish Li ne)\n⢠+1 551 285 1373 US (New Jersey)\n\nMeeting ID: 165 827 5045\nPass code: 905304\n\nFind your local number: https://bnl.zoomgov.com/u/ayKodW QQl\n\n---\n\nJoin by SIP\n⢠[email protected]\n\n---\n\nJoin b y H.323\n⢠166.108.98.42 (US West)\n⢠166.108.66.42 (US East)\n\nMeeting ID: 165 827 5045\nPasscode: 905304\n\n LOCATION:https://bnl.zoomgov.com/j/1658275045?pwd=l7gmWmQBCBYz5kw5RYHSsbq qvTn7A0.1 BEGIN:VALARM TRIGGER:-PT10M ACTION:DISPLAY DESCRIPTION:Reminder END:VALARM END:VEVENT END:VCALENDAR
