he keeps saying that. And then he keeps answering me. Beside the point. 
 Larry, what I am saying is that I don't give a shit if it's a placebo 
effect, a realignment of my yin, or little green footballs -- if it improves 
my chances of survival by 65%. Now, if you have a life-threatening illness, 
you may feel free to confine your doctor to remedies whose mechanisms are 
understood. I'll nominate you for a Darwin Award when the time comes.

Dana

 On 7/19/05, loathe <[EMAIL PROTECTED]> wrote: 
> 
> Did you kill file Dana?
> 
> Tim
> 
> > -----Original Message-----
> > From: Larry C. Lyons [mailto:[EMAIL PROTECTED]
> > Sent: Tuesday, July 19, 2005 4:55 PM
> > To: CF-Community
> > Subject: Re: the mechanism of action is unknown
> >
> >
> > violating kill file here.
> >
> > google the following (I don't see why I should have to do your
> > grunt work here).
> >
> > real simulator design
> > attentional control/placebo design
> > placebo response.
> >
> > Also get a good text on experimental design in Psychology at the
> > graduate level. Pedhauzer et al's Design Measurement and Analysis is a
> > good example. These books give quite a few ways of assessing these
> > effects.
> >
> > the idea is to present a valid, but bogus design. The problem is that
> > people are gullible and will believe almost anything if presented the
> > right way. In addition in research, generally people want to cooperate
> > and please the researcher. Therefore they can be very good at
> > determining the real objective of the study.
> >
> > There is not indication of anything you mentioned that does not fit
> > within a placebo response paradigm. Unless controlled for, for all
> > intents and purposes it esentially fits within a space cadet bs sort
> > of belief.
> >
> >
> >
> > On 7/19/05, Dana <[EMAIL PROTECTED]> wrote:
> > > All very true. But explain to me how you are going to test the
> > effect of the
> > > mind on healing in a double-blind study? This isn't something from the
> > > National Enquirer we're talking about... this is Lancet. Ergo,
> > the science
> > > is sound, or they would not have published it.
> > > On a slightly different topic there is also a problem with the current
> > > paradigm in that drug companies are being relied on for
> > research. Based on
> > > my adventures in the land of coumadin, I can assure you that a similar
> > > effect can be had with either ginko balboa or gingseng.
> > However, there is an
> > > issue of standardizing the dose, one, and monitoring the very
> > considerable
> > > side effects. Therefore, people with clotting issues are given
> > a substance
> > > best known for being a rat poison, rather than a substance best
> > known for
> > > improving memory, because there is a patent on the former and not the
> > > latter.
> > > Dana
> > >
> > > On 7/18/05, Jim Davis <[EMAIL PROTECTED]> wrote:
> > > >
> > > > > -----Original Message-----
> > > > > From: Dana [mailto:[EMAIL PROTECTED]
> > > > > Sent: Monday, July 18, 2005 5:57 PM
> > > > > To: CF-Community
> > > > > Subject: the mechanism of action is unknown
> > > > >
> > > > > A google of the above phrase turns up references to oral
> > > > > anticoagulants, interferon, anti-epileptic medication, mood
> > > > > stabilizers, and treatments for breast cancer, parkinson's and
> > > > > tuberculosis....
> > > > >
> > > > > conclusion - just cause it's not understood doesn't mean it's not
> > > > > medecine.
> > > >
> > > > Just because some things that work are not understood doesn't
> > mean that
> > > > all
> > > > things that aren't understood work. ;^)
> > > >
> > > > I know I'm harping on this but this is the reason for
> > double-blind studies
> > > > and control groups. People who don't know if their getting the real
> > > > medicine are dosed by doctors that don't know if they're
> > giving the real
> > > > medicine.
> > > >
> > > > It's to link the results to the proper cause: did the drug do what 
> its
> > > > supposed to do? If there's little difference between the test and 
> the
> > > > control groups then it seems clear that the drug just isn't
> > doing much.
> > > >
> > > > The actual method of action isn't as important. Determining
> > that for any
> > > > drug can be insanely painstaking as you're hunting down very 
> specific
> > > > bio-chemical effects in a vast system.
> > > >
> > > > What frustrates me is the blanket being thrown up: because some 
> things
> > > > aren't understood anything is possible.
> > > >
> > > > Comparing a well-tested, well-defined, double-blind proven
> > drug to any of
> > > > the ill-tested, loosely-defined therapies out there based
> > simply on the
> > > > lack
> > > > of complete understanding of the former is just unfair.
> > > >
> > > > Jim Davis
> > > >
> > > >
> > > >
> > > >
> > > >
> > >
> > >
> >
> >
> 
> 

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