Frankly, I wish that all bitch owners would be happy with direct AIs.  They
are our very first choice, followed by a hooded culture, followed last of
all by the run of Baytril. AIs are safe for the dog and the bitch, and the
litter size appears to be the same.  I find that a lot of bitch owners do
not have faith in the AI procedure.  Myra Savant


>From: Leanne Bertani <[EMAIL PROTECTED]>
>Reply-To: The Cavalier King Charles Spaniel List
><[EMAIL PROTECTED]>
>To: [EMAIL PROTECTED]
>Subject: [CKCS-L] antibiotics, etc
>Date: Thu, 20 Dec 2001 11:56:52 -0500
>
>There will certainly be varied opinions among veterinarians regarding the
>antibiotic issue, and here's why:
>
>The problem with prophylactic antibiotics is that the best culture is taken
>at the beginning of the season because the cervix is partially open.  There
>is no point in testing for mycoplasma in the vagina, because it is normal
>flora in the vagina -- you are looking for mycoplasma (or E Coli or
>whatever) in the uterus.  A culture done prior to the season is probably
>going to show nothing, or show vaginal flora, but tell you very little
>about
>the what's in the uterus, because the cervix is closed when the bitch is
>not
>in season.
>
>And suppose we do wait until the onset of the season to get the culture?
>Well, we have established that pelvic disease may take 2-3 weeks to treat.
>Since you are probably not going to get the culture results until well into
>the season, and conception takes place prior to 14 days into the season,
>well, you see the dilemma.  I know some people give Baytril to pregnant
>bitches, but you gotta wonder about its effect on cartilage development.
>If
>the infection is E Coli, then that may be sensitive to ampicillin, which is
>safe in pregnancy.  If the infection requires Baytril, I guess you could
>treat that season and wait to breed until the following season.  Al(Myra,
>maybe you could answer this one?  Why does your vet choose Baytril?  I know
>it's broad-spectrum, but if you are only worried about one bug --
>mycoplasma --how about erythromycin?  Next time you go in, ask if
>erythromycin would be sufficient?  Cindy, are you here?)
>
>As Barb mentioned, Baytril is not innocuous.  It is hard on the stomach,
>and
>can cause mental disorientation.  Vets call it "Baythrill", for the mental
>effects it has (Vets and breeders sometimes take their dog's meds........)
>
>My own personal opinion, for what it is worth, is that I would not mess
>with
>the cervix of a healthy bitch (there is an important protective factor in
>the cervical mucus -- see abstract below), and I wouldn't put her on
>prophylactic antibiotics because I wouldn't want to mess with the normal
>flora, which is also protective. As a stud dog owner myself (different
>breed), I understand the stud dog owner wanting to protect their dog.  I
>guess if I wanted to use Myra's dog bad enough, I might consider an AI.
>Interesting topic.
>
>Leanne
>
>
>
>
>Am J Obstet Gynecol 2001 Sep;185(3):586-92
>An in vitro study of antibacterial properties of the cervical mucus plug in
>pregnancy.
>Hein M, Helmig RB, Schonheyder HC, Ganz T, Uldbjerg N.
>
>
>Cervical mucus plugs from 56 healthy women in labor were studied by 2
>different antimicrobial assays: Analysis was done by overlaying the
>cervical
>mucus plug onto an agar plate with imbedded bacteria, and by radial
>diffusion assay with group B Streptococcus and Escherichia coli.
>
>RESULTS: In the agar overlay assay, there was complete inhibition of
>clinical isolates of Staphylococcus saprophyticus, E coli, and Pseudomonas
>aeruginosa and patient-variable partial-to-complete inhibition of
>Enterococcus faecium, Staphylococcus aureus, Streptococcus pyogenes, and
>Streptococcus agalactiae. In the radial diffusion assay, cervical mucus
>plugs had activity toward group B Streptococcus equivalent to 0.075
>microg/mL of gentamicin and toward E coli equivalent to 0.5 microg/mL of
>gentamicin. CONCLUSION: A low-molecular substance with antibacterial
>activity in the cervical mucus plug may protect the fetus against ascending
>infections.
>
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