For those out there who know stochastic processes better than me (and that is 
probably everyone), can you tell me if the following problem has an analogy in 
the stochastic process literature. If it does this will save me having to 
invent something:


1.       Suppose we have N dart boards (virus genomes) lined up

2.       We throw a dart (random virus sequence) at a specific dart board

3.       The dart hits that targeted dart board but also hits (my darts can hit 
many dart boards with a single throw) some arbitrary number of the other 
non-target dart boards (conserved sequences)

4.       When we start throwing darts we may target any number of different 
boards (first dart targeted at board 10, second dart targeted at board 3, third 
dart targeted at board 10, etc)

5.       We expect for any set of darts that there will be a small number of 
boards targeted each with a different frequency

6.       We expect (roughly) the non-targeted boards to be hit randomly

I want to have a formal mathematical model for deciding which boards (virus 
genomes) have been targeted and how many darts (random genome sequences) need 
to be thrown to make my decision.

Thank you

Bill Shannon, PhD
Associate Prof. of Biostatistics in Medicine
Washington University School of Medicine
660 South Euclid Ave, Box 8005
St. Louis, MO 63110

[email protected]/314-454-8356<http://[email protected]/314-454-8356>


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