Perhaps "un-morphometrics". In morphometrics we discard location, orientation, 
and size and analyze what variation is left - shape. Here it sounds like you 
want the opposite.  

Jim
-------
Sent remotely by F. James Rohlf,
John S. Toll Professor, Stony Brook University

-----Original Message-----
From: "Shannon, William" <wshan...@dom.wustl.edu>
Sender: "Classification, clustering, and phylogeny estimation" 
<CLASS-L@lists.sunysb.edu>
Date:         Tue, 15 May 2012 18:55:15 
To: <CLASS-L@lists.sunysb.edu>
Reply-To: "Classification, clustering, and phylogeny estimation"
              <CLASS-L@lists.sunysb.edu>
Subject: Re: clustering in a time series

Jim

I was thinking similarly that the goal is to keep the head of the person being 
imaged (using MEG) completely immobile.  If they are running multiple scans 
then the registration of one image with the next is greatly simplified by 
knowing the brain has not moved.

I also was thinking that morphometric techniques might be useful. Instead of 
transforming one set of morphometric measurements onto another set, they could 
use these to test that no transformation is required.

Marc, does this sound right?

Thank you

Bill Shannon, PhD, MBA (In Progress)
Professor of Biostatistics in Medicine
Washington University School of Medicine
Director, Biostatistical Consulting Center
314-454-8356

________________________________
From: Classification, clustering, and phylogeny estimation 
[CLASS-L@LISTS.SUNYSB.EDU] On Behalf Of F. James Rohlf 
[ro...@life.bio.sunysb.edu]
Sent: Tuesday, May 15, 2012 6:39 PM
To: CLASS-L@LISTS.SUNYSB.EDU
Subject: Re: clustering in a time series

I am not exactly what question is being asked. I assume the head is rigid. So 
the 3 distances should be invariant except for measurement error. To detect 
movement one would want to detect changes in the location of the 3 points in 
space and their orientation would also be of interest. Does that sound 
reasonable?
-------
Sent remotely by F. James Rohlf,
John S. Toll Professor, Stony Brook University
________________________________
From: Marc Lalancette <marc.lalance...@sickkids.ca>
Sender: "Classification, clustering, and phylogeny estimation" 
<CLASS-L@lists.sunysb.edu>
Date: Tue, 15 May 2012 21:05:15 +0000
To: <CLASS-L@lists.sunysb.edu>
ReplyTo: "Classification, clustering, and phylogeny estimation" 
<CLASS-L@lists.sunysb.edu>
Subject: clustering in a time series

Hello,

I was referred to this list by someone on sci.stat.math 
(https://groups.google.com/forum/?fromgroups#!topic/sci.stat.math/-bDEys5WTjk). 
 I apologize if this is not the right forum for this type of question.  I have 
limited stats knowledge and I've been doing some research to find a "good" 
solution to my problem.  I'll first describe what I want to do and then what I 
came up with based on some more or less fruitful research.  I'd appreciate some 
suggestions, tips, references to similar or "better" methods, etc.

I have 3-d motion data for 3 markers stuck on a person's head, while he/she is 
trying to be still.  The first step is making sure the markers did not fall 
off, so I calculate the 3 between marker distances across time and in what 
follows I basically treat that as a 3-d Euclidean vector, even though it's not 
Euclidean, but I'm not sure how else to combine these 3 distances...  (Also, 
later, I could ask the same questions about each marker's position to see if 
the person moved and in that case it is Euclidean 3-d space.)  I want to detect 
changes, and get a "good" partition of the time series into intervals based on 
when changes occurred, i.e. a list of roughly stationary intervals and an 
associated position for each interval.  I'm assuming there won't be many 
changes and that they would mostly be fast (i.e. step-like time series), but 
they could also be slow, in which case I'd still want to detect it and split it 
in chunks that are "mostly still", depending on the measurement error.

After some research, here's what I came up with.  My first idea was to use 3-d 
distances between samples adjacent in time to evaluate the measurement error, 
i.e. an approximation of the distribution if there were no movement (that's why 
the assumption of few changes is important).  Comparing that distribution with 
the distribution of all inter-point distances (or a subset: maybe all distances 
from the first point) would tell me if there was any movement.  I was thinking 
of using the Kolmogorov-Smirnov test for this.  Then I thought I could use a 
hierarchical clustering method based on the same idea.  Divisive since I expect 
few clusters.  I would recursively look for the boundary point in time that 
would maximize the KS test probability for the intervals on both sides 
(one-sided test since intervals that are unusually stationary would be "ok").  
Then I looked for something that would account for model complexity (thinking 
of reduced chi-square) and found the AIC.  Maybe I could interpret the combined 
KS probabilities as a likelihood for that particular partition and use the AIC 
to decide when to stop dividing the intervals.

This is what I came up with based on what I found in my research.  Almost all 
of the concepts and methods I mention I didn't know about a week ago, so I 
assume the resulting amalgamation has quite a few "weaknesses" even though it 
might work.  I'd be happy to hear what knowledgeable people would have to say 
about this.  Feel free to contact me directly by email.  I'll also monitor the 
list for replies.

Thanks!

Marc Lalancette
Research MEG Lab Project Manager
Program in Neurosciences and Mental Health, Department of Diagnostic Imaging, 
The Hospital for Sick Children, Toronto, Canada

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