Hi
Just to clarify a little (I have no major knowledge) but from what I 
have read Der 9 chrom. is not so bad in the Gleevec era as it was 
prior to Gleevec.  Also, Der 9 is not a mutation, but a chromosomal 
abnormality.  I know of at least two cml'ers in the UK who have this 
abnormality and they have had wonderful results on Gleevec thus far, 
reaching CCR.  Hope this helps you to not worry too much about it.
Best wishes
Annette
Husband Rich dx May 2003
P Loop mutation M244V detected May 2004
Off Gleevec since Sept 2004, just on Hydroxyurea
Still 100% PH+
Awaiting BMS Phase 2 starting in London, UK
Watch this space!

--- In [email protected], Yoli <[EMAIL PROTECTED]> wrote:
> My boyfriend has this mutation, but the doctor won't give us a 
straight answer, so I would also like to know.
> 
> susanna chung <[EMAIL PROTECTED]> wrote:Help! Can someone tell me 
if those with Derivative 9
> chromosome deletion has poorer survival rates than
> those without? Dorothy emailed me an article that
> disputes this, but other articles I've seen say
> otherwise. 
> 
> There was one article published in England that saide
> it even worsens your prognosis if you have a stem cell
> transplant? Is that true?
> 
> Susan
> 
> 
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