Hi, I thought I would pipe in here because I also had the chromosome 
9 deletion at diagnosis.  I really didn't have too much time to worry 
about it because Dr. Druker told me a few months after diagnosis that 
it was too early to tell if it would be a prognostic factor in the 
gleevec era.  I took that as a positive because not knowing for me at 
the time was better than the picture in the interferon era.

I also was not told that it had any negative prognostic outcome for a 
bone marrow transplant.  But, I had never gone into depth on that 
route, because I'm one of those odd ducks (43 year old white american 
female) who has no known donor in the world.  So I guess I looked at 
it like at least I don't have to make that decision.

But, I have to tell you that response to treatment is the only thing 
anyone should really worry about.  The problem with deletion 9 and 
interferon is people didn't usually get a good response.  I have.  I 
am undetectable by PCR 3 years out.  I just had another PCR today and 
hopefully I will keep those great results.

Getting to zero is what the goal is, with or without dletion 9.  Once 
you do, it's kind of a mute point, because if the cml isn't there 
than the deletion 9 won't be there either.

HOpe this helps someone,
love,
Susan King
dx 8/2001, age 40
600 mg
PCR undetectable, age 43





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