--- In [email protected], "Gale" <[EMAIL PROTECTED]> wrote:
> 
> Hello Jim,
> 
> Welcome to the group!  This group has been my greatest source of 
> information since my diagnosis in March, 2000.  Glad you found it.
> 
> For the 14 months prior to Gleevec approval, I was also on 
interferon 
> and hydrea.  Hydrea did absolutely nothing. Interferon, at first, 
> reduced my PH+ cells from 98%, down to 12%, but then they climbed 
> back up again to 87%, while my weight dropped to 90lbs.
> 
> Gleevec has fattened me up a touch, but nothing that exercise and 
an 
> occasional diuretic can't remedy. <big grin>
> 
> How long have you been on 600mg? Any change in your PH%? 
> 
> Regards,
> Gale Bacon
> dx'd 3/00
> Gleevec 400mg, starting 6/01
> molecular remission 9/01

Hi Gail,
Thank your for your welcome message.  I am glad to be onboard with 
this group.  Didn't you just love interferon, and Hydrea...oh, the 
good old days. lol  To answer your question, I have been on 600mg 
now for about 3 months.  My latest FISH test my PH% to be 36%..the 
big problem is that I have progressed from 500mg to the 600mg and 
have been showing slow progress to what my Dr. calls (toxic)to my 
blood. Pancytopenia..all of my blood counts are dropping steadily 
even with the support of Procrit.  My lowest PH% during the dosage 
increase has been 27%.  I am now on my way back down to the 400mg 
level.  I think that I will be accepted in a BMS phase 2 trial in 
the next few months...in the Pittsburgh, PA area.

Take care
Jim Beck
dx 8/2001
age 63
600 mg IM





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