Hi Happymomag,

 

Sorry to hear about Terry’s problem with gout and uric acid levels.  I just recently had a severe gout attack and went to my primary care physician, he prescribed indocin (a nonsteroidal anti-inflammatory) to relieve the inflammation brought on by gouty arthritis.   After taking the anti-inflammatory, it took three days before the pain to subside and another two weeks for the swelling to go away.    

 

I have had two gout attacks since I was diagnosed with CML (9/25/04).   I can’t say that the attacks are more severe due to Gleevec or CML side effects, but it does appear to take longer for the pain and inflammation to go away.

 

Besides elevated uric acid levels, stress is also a primary contributor.   I was diagnosed with gouty arthritis at an early age (23).  At the time my physician attributed my gouty arthritis to stress and an elevated uric acid level.   I can attribute both of my recent attacks to stress.

 

The reason you don’t want someone take allopurinol in the middle of a gout attack is that a sudden drop in uric acids will only exacerbate the gout attack.  A too low or too high uric acid level can contribute to a gout attack.  

 

You should talk Terry’s primary care physician about alternative medications, Advil can cause decreased liver functions and Gleevec is already hard on the liver.

 

Hope this helps.  Let me know if you need more information.

 

Peter

Dx:  9/25/04

Gleevec:  10/04 – 400mg

 

 

 


From: happymommag [mailto:[EMAIL PROTECTED]
Sent: Friday, February 04, 2005 10:44 PM
To: [email protected]
Subject: [CML] Terry & gout

 


ok, folks....Terry's gout seems to be getting worse....it is 12:30am
& he is yelling out in pain.....I looked at WebMd & it suggested
something like Advil (NSAID)....so I gave it to him....800mg

He has been on Allopurinol for a few weeks.  WebMD said something
along the lines that if you have have not been taking the drug, don't
start during the middle of an attack.   But since his uric acid level
was already increasing previous to taking Allopurinol, I am not sure
whether I would call his increasing pain from several weeks ago an
attack...to where tonight it is an hard attack due to severity of
pain.  

okay...well I think the Advil must be helping...he is calming down &
not screaming out any more.   argh!!!    but very thankful!!   Now,
all my children are up & kind of wondering what to do.  They were all
trying to find the heating pad, get Terry the Advil, and worrying.  
I just told them now to watch some TV or play video games while I de-
stress!!!   I did explain that I might take Terry to ER, but we do
know what is wrong & have an idea of what help he will need, so they
wouldn't worry about the unknown.

after talking with a friend whose hubby as ALL......well, it seems
with CML....as you work through the disease...the side effects cause
other side effects, so you can never just be "okay".....is this a
fair assessment?? 

update....our financial aid app for MD Anderson was submitted, now we
are awaiting approval....& might now by Mon or prob Tues....then they
said he would have an appt in 3 weeks.   I also talked to the Patient
Advocate Foundation to get app forms for some of the various
prescriptions that we are getting prescribed.  

Terry worked today, but was limping....and I could tell he was going
down fast.....he also has some upper respiratory problems on top of
it all. 

He says the constant shooting pain has subsided.....whew!!!   He is
still uncomforatble, so I guess watch & wait.

Lora....a very worried wife





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---------------------------------
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