Hi Marilyn

>From my understanding, you are in major molecular remission but not complete 
>molecular remission, since it is still detectable at .0025%.  One has reached 
>complete molecular remission when levels are undetectable.  The sensitivity of 
>the test should be known, both for your test last year (when you reached zero) 
>and for this test, because perhaps one test was more sensitive than the other. 
>The most sensitive tests can detect one cell in 100,000 to 1 million cells.  
>When a real-time PCR test does not show any detectable ABL-BCR cells, then a 
>nested PCR test is done.  
At any rate, you are definitely doing well.  You should not be concerned unless 
that .0025% starts to rise.

I think that the frequency that doctors check bloodwork varies. Every two 
months does not sound too long, but if you are uncomfortable with that, ask him 
to check it once a month. And I would still have a BMA or BMB every 6 months, 
if I were you, though I think it is not uncommon to wait 1 year between 
BMA/BMBs once one has reached MMR or PCRU.

Libby
dx 8-24-04
PCRU March 05
800mg Gleevec/peg-intron/lukeine





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