Libby , Hi I see you take 800 mg. of  gleevac can you tell me are your side affect any different than that of one who take 400 mg,? you see my husband is go to start to take 800mg. very shortly and I' m a little worry for him .You ask why are they changeing his med from 400 to 800 well the Dr.s think 400mg is not enough for a man 5'11 and 237pounds. so can you give some feed back or any one for that matter thank you
Maggie-caregiver
Sergio-cml10-13-03
gleevac 400mg

Libby Scrivner <[EMAIL PROTECTED]> wrote:
Hi Marilyn

From my understanding, you are in major molecular remission but not complete molecular remission, since it is still detectable at .0025%.  One has reached complete molecular remission when levels are undetectable.  The sensitivity of the test should be known, both for your test last year (when you reached zero) and for this test, because perhaps one test was more sensitive than the other. The most sensitive tests can detect one cell in 100,000 to 1 million cells.  When a real-time PCR test does not show any detectable ABL-BCR cells, then a nested PCR test is done. 
At any rate, you are definitely doing well.  You should not be concerned unless that .0025% starts to rise.

I think that the frequency that doctors check bloodwork varies. Every two months does not sound too long, but if you are uncomfortable with that, ask him to check it once a month. And I would still have a BMA or BMB every 6 months, if I were you, though I think it is not uncommon to wait 1 year between BMA/BMBs once one has reached MMR or PCRU.

Libby
dx 8-24-04
PCRU March 05
800mg Gleevec/peg-intron/lukeine





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