Hailed as a beacon for the future of cancer drug development when it was launched in May 2001, Novartis's Glivec has achieved a dominant position in the chronic myeloid leukemia (CML) market and garnered worldwide sales of $1.6billion in 2004. However, while Glivec remains the gold standard treatment for CML, the emergence of Glivec drug resistance has left a void in the market.


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