|
Chronic myeloid leukemia is a myeloproliferative disorder characterized by
the presence of the Philadelphia chromosome, t(9:22). Extramedullary blast
crisis is a rare event. Imatinib mesylate has become the treatment of choice,
especially for patients for whom allogenic stem cell transplantation is not an
option. Imatinib produces complete cytogenetic responses in excess of 80%.
However, the penetration of the drug and its metabolites into the CNS (Central
Nervous System) is poor. Hence for patients who are on prolonged imatinib
therapy and continue to have complete cytogenetic responses, the central nervous
system may become a sanctuary site. We report a patient who had a complete
hematologic and cytogenetic response and presented with headache and vomiting.
New! Sign up for local CML support group meetings in your local community at http://cml.meetup.com Apply for Commercial Real Estate loans online and submit your deal to dozens of hungry lenders in just minutes. Loan programs for all types of business and commercial real estate. Apply anytime at http://realestatezoo.com CML (Chronic Myelogenous Leukemia Support List) --------------------------------- Part Of CMLHope.Com An International Community Of CML Patients For more information: http://cmlhope.com Post Message: [email protected] Subscribe: [EMAIL PROTECTED] Unsubscribe: [EMAIL PROTECTED] Change To No Mail/Web: [EMAIL PROTECTED] Change To Digest: [EMAIL PROTECTED] Change To Email: [EMAIL PROTECTED] List Help: [EMAIL PROTECTED] CML Group Web Site http://groups.yahoo.com/group/CML YAHOO! GROUPS LINKS
|
