Re: [CML] Update AMN107

Mon, 03 Oct 2005 12:34:11 -0700

How did you know the Glivec was killing off your good bone morrow?  I think
this may be happening to me.
 
Dan


-----Original Message-----
From: char fisher <[EMAIL PROTECTED]>
Sent: Sep 26, 2005 6:31 PM
To: [email protected]
Subject: Re: [CML] Update AMN107

Narayan :)
The same thing happened to me the glivec not only didnt work for me but i found out the 600mg was killing off my good bone marrow. I found out by listings online and you can ask your doc if he knows of any around your area. I have to drive 3 hours to get to the one in Buffalo but really for me its the last option before bmt  so its well worth it. Good luck I hope and pray you find one and it kicks butt :)
                                                                                         Char :) :) :)

Narayan Basel <[EMAIL PROTECTED]> wrote:
I would like to joine for AMN 107 please tell me what to do In my case glivec is not working properly
thanks
Narayan Basel


char fisher <[EMAIL PROTECTED]> wrote:
Hi guyzz :)
Fri. I finished my pretesting for the amn107. I should be starting it some time in the next 2 weeks. Im excited and scared I know a lil info on it if anyones interested. Ill be in phase 2 at Roswell in Buffalo. was thinking about starting a journal on it.
 
                                                                                                          Char :) :) :)
                                                 

Cheryl-Anne Simoneau <[EMAIL PROTECTED]> wrote:
Update from Novartis news release on AMN107
 
This excerpt was taken from a lengthy press release regarding Novartis's other drugs for Diabetes and cardiovascular health.  Rather than post the entire article, I thought I'd just send the paragraph that regards CML...
 
Cheers,
Cheryl-Anne
 

-- AMN107, a novel investigational oral compound being developed as a new treatment for advanced chronic myeloid leukemia (CML) patients, is planned to be submitted for regulatory approval in 2007. Enrollment in a pivotal Phase II study of patients with CML resistant to Gleevec/Glivec began in April 2005, with a Phase III study in chronic phase CML patients initiating treatment planned to begin in the first quarter of 2006. AMN107 further expands the Novartis franchise for helping patients with CML and GIST (gastrointestinal stromal tumors).

 

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