How true that you must consider every aspect when deciding what 
treatment is best for you.  Transplant certainly shouldn't be taken 
lightly by any means, but I don't think anyone really takes the 
decision to have a transplant lightly.

And just to be fair, Gleevec isn't magic or gold for everyone who 
takes it.  It failed my husband.  He was only 29 years old and our 
first child was only 9 days old when my husband was admitted to the 
hospital in blast crisis.  The day my son was born, my husband had a 
BMB that was clean.  It happened that fast...lightening quick and he 
was in the final stages of CML...it was in his marrow and in his 
lymph nodes.  Nine days was all it took.  We had no choice but to 
opt for transplant.  We didn't have the time to wait for all of the 
wonderful options that are on the horizon.

Would we have chosen transplant had we had the choice of some of the 
other drugs/clinical trials/etc...?  Probably not, a BMT was an 
option right from the start, as it is for anyone, but we had Gleevec 
and chose that...in fact, we didn't even want to consider the 
possibility of a BMT...BUT I still thank God every day that a BMT 
was an option available to us.  Was it easy?  No, it was pure hell.  
Is the recovery over?  No, we still deal with things.  But we've 
been blessed.  My husband has had some GVHD, but thankfully, it has 
been very mild and hasn't been life threatening.  He is now at 
school full-time pursuing a Ph.D. and works part time as a graduate 
assistant for the graduate school.  Most people who know him at 
school have no idea that a year ago, he was getting ready to start 
his pre-transplant regimen of total body radiation and 
chemotherapy...they have no idea he's had a transplant.  He is 
here to watch his son grow and to be a wonderful Daddy.  We got to 
celebrate our 6 year wedding anniversary this past June and will get 
to celebrate more in the years to come.

By the way, his transplant was an unrelated mismatched donor, a 9/10 
match...certainly not the most ideal situation, but again, we had no 
choice...it was the only match he had.  None of the doctors at our 
transplant center said that he would be cured from a BMT (it is only 
a POTENTIAL cure).  They were very honest and upfront with all of 
the risks and with the fact that he could relapse even after BMT; in 
fact, he's at higher risk for relapse because he was in blast crisis 
before he had the BMT.  But it is also true that he could remain 
leukemia free as he is right now.  He's had four PCR's since his BMT 
and there is no trace of CML.  We just got the results from the most 
recent one a few days ago.  I choose to believe that he will 
continue to remain free from CML, that he will continue to get 
healthier and healthier every day as he has done since the BMT.  The 
road to recovery is long and hard, but he has traveled it well.

I am not touting BMT as a magic cure or even as the choice everyone 
should make.  We know people personally who didn't make it through, 
it has been very hard.  But a BMT CAN be a good thing.  It isn't an 
evil thing that is a guaranteed killer.  My husband is proof of that 
and I know others who are proof of that as well.

Just wanted to tell another side of the story.  Not only do I thank 
God every day for the fact that my husband is doing so well, but I 
thank Him every day for the fact that there are so many options out 
there for people with CML...that there are new drugs, that there are 
new vaccines, that there are new treatments, and that there is 
Gleevec.  I pray that everyone facing CML will research everything 
available to them, will make the best choice based on their personal 
situation, and will fight the good fight (and win!) to beat this 
terrible disease.

All the best to you,
Karly

--- In [email protected], IAintFinishedYet <[EMAIL PROTECTED]> wrote:
>
> Regarding: BMT
>    
>   It is being 'tooted' as a CURE by the transplant doctors and 
specialists for statistical purposes. It is not a cure when we have 
brothers & sisters dying who were living the Gleevec life. 30% in 
1st 3 months, over 50% the 1st year.
>    
>   We have a Chronic Disease, brothers & sisters have survived 
since 1998 with our gold. We have the other drugs, trials, the 
vaccine and research on the horizon. We want the 'quick fix', but a 
BMT is not a cure when it fails and we're living the Gleecec life 
again. GVHD cannot be taken lightly, it's a killer. So very much to 
consider, but every aspect in life should be considered. 
> 
> 
> "K"
> "I AIN'T FINISHED YET"!!!
>








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