Scientists in the U.S. believe they have identified a new pathway in the progression of chronic myelogenous leukemia (CML).
They have also discovered that an extract from the root of a common ornamental plant can suppress the process.
The exciting new extract is forskolin, which comes from the root of the plant coleus forskohlii, a native of India that is used in the U.S. as an ornamental plant.
Their findings may suggest new treatment options for the estimated 4,600 people in the United States who are expected to develop CML this year, in particular those in the advanced stages of the disease, or those who become resistant to the commonly used drug Gleevec.
Early results on CML patient cells both in culture and in mice have apparently shown that forskolin reduced the cancer cells' ability to grow by up to 90 percent.
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