Glad you have received some positive news Jeanie. Are you waiting for more results, or do these results allow you to relax a bit? God bless, Kathy
On Feb 4, 3:30 pm, [EMAIL PROTECTED] wrote: > Thanks, > I thought it sounded good but my platelets are still a little high; 509 on > this test; WBC 7.9. > I can't understand why on some test there are no abnormal cells and on other > test there are. > It's confusing. > Thanks again, > Jeanie<3 > In a message dated 2/4/2008 11:00:20 A.M. Pacific Standard Time, > > [EMAIL PROTECTED] writes: > > No abnormal cells is good. > > Polyclonal is good. It means a diverse population of lymphocytes > instead of an expansion of a single clone (leukemia). Most > Lymphocytic leukemias are B-cell in origin > > Granulocytic cells are your Neutrophils, Eosinophils, and Basophils. > No problems there. Immature granulocytic (aka myeloid) cells which > can be indicative of other leukemias can be detected by flow > cytometry. > > In cytometry, your cells are divided among a bunch of tubes and test > reagents are added that have fluroescent dyes attached. Each tube is > labeled with the names of the tests and about 6 can be added to each > tube. Then the cells are sucked up into the cytometer and passed thru > a laser beam. Cells are measured by the way they bend the laser light > and also what type of flurescence light they emit. > > Gating is just the way the results are sorted out on the computer. > Each cell that is analyzed on the cytometer (it can read about 10,000 > a second) are stored in a computer file and its one file per test > tube. The technician then goes back in the computer and puts gates > (boxes) around the cell populations and asks the computer to show the > results just for the cells in the gate. On a cytometer, the cell > populations form kind of an arc on the screen with the lymphocytes in > the lower left, the monocytes mid right, and the granulocytes in the > upper middle to upper right. The idea with gating is just to look at > what is of interest depending on the test reagents that were put into > that tube. If the tube had no lympocyte-specific reagents in it, then > there is no need to even count the lymphocytes in the analysis. > > A common test for clonal B-cell expansion is to test CD5 and CD19 > (CD20) in the same tube. CD5 is usually only on T-cells. CD19 is on > all B-cells and CD20 is only on mature B-cells. Every person with > Chronic Lymphocytic Leukemia will have leukemia cells that exhibit > both CD5 and CD19 (or CD20) on the same cell. That is not normal. If > each reagent was done separately, one might be able to infer that > something was wrong since the % of B-cells in the blood was way too > high but this simple combination confirms the diagnosis immediately. > Cytometry can be quite useful as a screening tool of the blood. > > This report looks great. > > On Feb 4, 1:01 pm, [EMAIL PROTECTED] wrote: > > > > > > > > > Hi all, > > Here is the results of the FLOW CYTOMETRY REPORT done on my Peripheral > blood. > > IMMUNOPHENOTYPE REPORT > > SPECIMEN : Peripheral blood > > > INTERPRETATION > > There is no immunophenotypic evidence of an abnormal population of cells. > > IMMUNOPHENOTYPE (of relevant population); Polyclonal B-lymphocytes, normal > > T-lymphocytes and granulocytic cells are identified. > > ANALYTICAL GATING: > > Gating was performed on the granulocytic, blast, monocytic and > lymephocytic > > region > > MORPHOLOGY: > > Review of the peripheral blood smear demonstrates no evidence of > circulating > > abnormal cells > > CLINICAL DATA: > > The patient is a 69 year old female with history of thrombocytosis and > > leukocytosis > > Can someone explain this to me. > > Thanks, > > Jeanie<3 > > **************Biggest Grammy Award surprises of all time on AOL Music. > (http://music.aol.com/grammys/pictures/never-won-a-grammy?NCID=aolcmp0... > 48)- Hide quoted text - > > - Show quoted text - --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [EMAIL PROTECTED] For more options, visit this group at http://groups.google.com/group/CMLHope -~----------~----~----~----~------~----~------~--~---
