Good morning Anjana and all our CML warriors,
I didn't think I had heard of anyone on the list talking about the flow  test.
I was surprised when I got it as I thought it was a PCR test.
However,it was interesting.
Something else in my recent tests is that my RDW have come down to  normal.
They had been over the limit for a long time.
Here is the last result of my CBC test:
02/04/2008
WBC                                       5-0
RED BLOOD CELL COUNT      4.20
HEMOGLOBIN                        12.6
HEMATOCRIT                         37.5
MCV                                      89.4
MCH                                      29.9
MCHC                                    33.5
RDW                                    14.8
PLATELET  COUNT                                     472 H
ABSOLUTE NEUTROPHILS 3080
ABSOLUTE  MONOCYTES                           130 L
ABSOLUTE EOSINOPHILS  165
ABSOLUTE BASOPHILS        20
NEUTROPHILS                       61.6
LYMPHOCYTES                     32.1
MONOCYTES                          2.6
EOSINOPHILS                        3.3
BASOPHILS                           0.4
So as you can see, the only thing out of wack is my platelets and my  
monocytes.
The monocytes help fight infection and they had never been low  before.
All in all, I seem to be doing good.
Blessings everyone and thanks Angana for all the input.
Jeanie<3
 
In a message dated 2/6/2008 1:20:10 A.M. Pacific Standard Time,  
[EMAIL PROTECTED] writes:

Dear  Jeanie,

My husband's doctor never did a flow cytometry test, he  was
diagnosed in chronic phase and remains in chronic phase.  I have  a
friend whose husband was diagnosed in advanced phase and his  doctor
has the flow test done periodically to check for blast or  immature
cells.  So you are very correct in your thinking.  Since  your doctor
thought from your high platelet counts that your disease may  be
progressing, he did the flow cytometry test which checks for  immature
cells.  Thankfully, you have none.

You referred  to your report which said 'thrombocytosis and
leukocytosis', that means  high platelet count and high white blood
cell count.  So, again, you  were referred to the flow test because
your platelets went  up.

Now that you know that you remain in chronic phase and there  are no
immature cells as well as the platelet counts are coming down on  the
600mg Gleevec, discuss with the doctor to do PCR monitoring after  3
months.  By 3 months, you will know how the higher Gleevec dose  is
working for you.  I think you said that another PCR is scheduled in  3
months.  That is fine.  You need some time to see how the  higher dose
is working.  Most doctors would do another PCR in about 3  months.
Always do a quantitative PCR test which shows numbers to track  your
disease.  And the PCR giving a number but a low number is fine  because
very few patients test negative by the sensitive PCR test.   But as
long as your PCR numbers are low, your risk of relapse is very  low.
You can compare the PCR number to the ones you had on 400mg  Gleevec
and see if there is lower disease load on 600mg Gleevec.

So,  again, you are doing fine, keep a watch on your platelet counts
and other  blood counts and wait for the next PCR test and result.  If
the PCR  test shows a downward trend to low values, then all is fine.

I am very  happy for you that your platelet counts are coming down on
the higher dose  of Gleevec.  You rest easy now.

Love,
Anjana


On Feb  6, 12:31 am, [EMAIL PROTECTED] wrote:
> Hi and thanks,
> I  just got my CBC report and my platelets are coming down, which is  good.
> They were 472 and the WBC is 5.
> The only thing out  of balance other than the platelets was the monocytes  
> which  were low; 130.
> This could be due to the high dose of Gleevec I am now  taking.
> About the PCR test; I ask the Dr for a PCR and he had me take  the FLOW one 
 
> instead. Go figure.
> I think he did it  because of the increase of platelets.
> All in all, I'm doing  good.
> Blessings,
>  Jeanie<3








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