Novartis has several patents on Gleevec, but generally the main patent
expires in 2015 (it was extended from the original expiration date of
2013). As mentioned, it was granted "orphan drug" status, meaning that
since it has a relatively small population that requires such a drug.
Patent law is more favorable to companies that invest in development
of new drugs to fill these "orphan drug" needs.

By the way, this also explains something about Sprycel and Tasigna.
Sprycel is made by a competitor of Novartis (Bristol Myers Squibb), so
it had to work differently than Gleevec, and it does.  But Tasigna is
made by Novartis, and it works like Gleevec, only with a stronger
binding capability.  If Tasigna had been made by another company, it
would have violated the Novartis Gleevec patent.


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