Zavie...I am still confused about the log reduction scale vrs the absolute  
pcr rating.  If you are at a pcr of 0.05 isn't that good regardless of what 
 the log reduction was?  Thanks for all your great work in keeping us in 
the  loop!  Regards, Tom in KY
 
 
In a message dated 1/23/2010 11:16:28 P.M. Eastern Standard Time,  
[email protected] writes:

Hi Daniel,
 
Whose idea was it to try and get to PCRU? All the literature says that  
once you reach a 3 log reduction your chances of relapsing with your CML are  
the same as if you reached PCRU.
 
Zavie


On Tue, Jan 19, 2010 at 4:15 PM, daniel <[email protected]_ 
(mailto:[email protected]) >  wrote:

hi all,
i recently switched to nilotinib (tasigna), in  an effort to get my pcr
down to zero (had decent response on gleevec, but  wanted something
more aggressive to try to get down to zero). anyway, i  started
nilotinib about 7 days ago and have developed a rash oAll the  literature 
says that once you n my face that
looks like a moderate  sunburn, as well as a really intense itch on my
scalp.  anyone have  any tips for managing these side effects? they are
not intolerable, but  are quite annoying! any advice would be  much
appreciated.

thanks,
daniel

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-- 
Zavie Miller (age 71)
67 Shoreham Avenue
Ottawa,  Canada, K2G 3X3
dxd AUG/99
INF OCT/99 to FEB/00, CHF
No meds FEB/00  to JAN/01
Gleevec since MAR/27/01 (400 mg)
CCR SEP/01. #102 in Zero  Club
2.8 log reduction Sep/05
3.0 log reduction Jan/06
2.9 log  reduction Feb/07
3.6 log reduction Apr/08
3.6 log reduction  Sep/08
3.7 log reduction Jan/09
3.8 log reduction May/09
3.8 log  reduction Aug/09
e-mail: [email protected]_ (mailto:[email protected]) 
Tel:  613-726-1117
Fax: 613-482-4801
Cell: 613-282-0204
Yahoo ID:  zaviem

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