hi guys,
thanks for your responses. true to Jeanie's suggestion, my rash has
thankfully subsided and the itch has declined to a mild level.

zavie, in regard to your question, the decision to switch drugs was
the product of a lot of consideration with my hemotology oncology team
at unc hospitals with additional input from drs. druker (OHSU), talpaz
(UM) and cortez (MD Anderson). basically, my intention is to attain 0
pcr and maintain it for a couple of years, try to eradicate the
remaining stem cells using a very aggressive regimen (probably a
combination of TK inhibitors and interferon) and then move to a
"maintenance dose" or discontinue therapy entirely. it is an
unorthodox approach and not consistent with current guidelines for CML
treatment, but i pushed very vigorously for a more aggressive approach
and this is what we decided on.

best wishes,
daniel

On Jan 19, 4:15 pm, daniel <[email protected]> wrote:
> hi all,
> i recently switched to nilotinib (tasigna), in an effort to get my pcr
> down to zero (had decent response on gleevec, but wanted something
> more aggressive to try to get down to zero). anyway, i started
> nilotinib about 7 days ago and have developed a rash on my face that
> looks like a moderate sunburn, as well as a really intense itch on my
> scalp.  anyone have any tips for managing these side effects? they are
> not intolerable, but are quite annoying! any advice would be much
> appreciated.
>
> thanks,
> daniel

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