Thanks Lisa for your valuable inputs on this subject. Kindly let me know the name of the Physician who decided to lower the dose of Gleevec to overcome this side effect.
Take care!! Anil On 2/24/10, [email protected] <[email protected]> wrote: > > My daughter, who is 14, also experienced a pronounced slowing of growth > after starting Gleevec. Prior to her diagnosis with CML, she always > measured in approximately the 60th percentile for height. Two years after > starting on Gleevec (400 mg), at age 9, she had really not grown at all and > her height percentile had slipped to below the fifth percentile. Since she > was PCRU, we decided, after consulting with her oncologist, to lower her > dosage to 300 mg in order to see if it would help with the growth problem. > For the first year, her growth rate did not improve much. But in the last > two years, she has had a wonderful growth spurt, growing nearly five > inches. She will still never probably reach the height she would have had > she not been on Gleevec, but she will probably end up at around the 15th > percentile for height. She now weighs 85 pounds and is just over five feet > tall. She is very healthy and active in several sports. > > I do believe that the reduced dosage really helped with the growth problem > and my daughter has remained PCRU. I believe that the standard Gleevec > dosage for the pediatric population in 240 mg per meter squared of body > mass, but many children are put on a much higher dose. I have also heard > from other parents that Gleevec seems to cause children to experienced > delayed growth. It may be that yoru son's growth is just delayed, but that > he may eventually catch up to his normal growth curve. Physicians can > often tell you how much more growing your son is expected to do by looking > at x-rays of his bones. > > Hope this helps. > > Take care, > Lisa > > > > > -----Original Message----- > From: anil nagpal <[email protected]> > To: [email protected] > Sent: Tue, Feb 23, 2010 12:26 pm > Subject: [CMLHope] Gleevec side effect on Kids > > My son who is 13yrs old now , is on Gleevec 500mg for the last 5 yrs. We > feel that his height ( 136 cm ) as of now is not proportionate to his age > .If anyone has experienced similar problem please share the experience with > comment to overcome this side effect. > > Anil > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope -- Regards Anil Nagpal -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope
