Hi Peter, It seems as though the "achy hands" is not isolated to Sprycel; many are experiencing the same thing on all of the TKI's. I was just hoping to maybe get a few Lot number comparisons for the Sprycel.
And yes, Tasigna needs an acidic environment to absorb properly, as does Sprycel, so I think I like your theory of the water diluting the acid in your stomach. Low acidity likely leads to low absorption<http://www.leukemiasurvivor.co/2013/08/absorption-of-medication-could-this-be.html>which for me, led to an increase in PCR; now that I am taking the Sprycel with Bragg's vinegar, my PCR is negative, but my side effects have increased<http://www.leukemiasurvivor.co/2013/12/sprycel-and-musculoskeletal-pain.html> . Hopefully today will be a better hand day! Michele On Tue, Apr 1, 2014 at 4:42 AM, Peter <[email protected]> wrote: > Hi Michelle. > When I was on Gleevec, I had lots of bone pain, but never in the hands. > Now, after two years on Tasigna, I noticed that for the last year or so my > hands are just killing me. The pain is in the joints and sometimes in the > muscles too. > My former "claws of steel" are now having trouble opening a pickle jar! I > never connected this to the Tasigna, thinking it is old age or arthritis, > etc. > Thanks for digging this up; it may shine a new light on this problem. > > While I have the attention of your keenly analytical mind, here is a > thought on the subject of drug absorption: > My doc always tells me to drink lots of water and specifically, to swallow > the Tasigna with a whole glass of water. > If higher stomach acidity equals higher absorption, how much sense does > that make? Wouldn't the water dilute everything in the stomach and thereby > lower acidity? > > .....just thinking out loud........ > > Peter > > > > On Monday, March 31, 2014 7:20:29 PM UTC-4, Michele, Loves to Dance! wrote: >> >> Hi All, >> I have written a post regarding hand pain, as there seem to be so >> many people on the FaceBook groups that are suffering from it; everyday >> there are 5 or 6 new people. >> >> I contacted Bristol Myers Squibb, as i am on Sprycel. Please read the >> post if you are suffering from hand pain. >> >> CML Hands: What the >> Heck?<http://www.leukemiasurvivor.co/2014/03/cml-hands-what-heck.html> >> >> Blessings to all, >> Michele >> >> >> -- >> [email protected] >> www.LearntoBallroomDanceOnline.com >> > -- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope > --- > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > For more options, visit https://groups.google.com/d/optout. > -- [email protected] www.LearntoBallroomDanceOnline.com -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. For more options, visit https://groups.google.com/d/optout.
