Resonant Sensors on CMOS for Chemical and Biological Applications

Thursday, February 20, 2014
8:45am - 9:45am
KEC 1007

Matthew Johnston
Bialanx

Abstract:
Merging chemical and biological sensors with modern circuits and systems has 
the potential to push complex electronics into low-cost, portable detection 
platforms. This greatly simplifies system-level instrumentation and extends the 
reach of such technologies out of the lab and into the field. At the same time, 
the rapid evolution of MEMS and NEMS sensors has enabled jump-shift improvement 
in sensitivity and throughput, even as cost, size, and system complexity have 
decreased. In this talk, an emerging resonant sensor platform and developed 
applications will be discussed, and future research directions will be 
presented.

A drive toward label-free, array-based chemical and biological sensing has 
motivated the development of piezoelectric resonators on CMOS. We have 
established a method for monolithic fabrication of unreleased, low GHz, 
thin-film bulk acoustic resonators (FBAR) directly atop a custom CMOS 
substrate. This device is analogous to a quartz crystal microbalance, where 
selective analyte binding causes a proportional decrease in resonant frequency. 
I will present the design and implementation of the complete FBAR-CMOS array, 
as well as experimental results of volatile organic compound (VOC) 
quantification using polymer-coated sensors. I will also discuss ongoing 
efforts to extend this platform to a clinical application in radiation 
biodosimetry.

Speaker Biography: Matt Johnston received his B.S. degree in electrical engineering from the California Institute of Technology (Caltech) in 2005, and his M.S. and Ph.D. degrees in electrical engineering from Columbia University in 2006 and 2012, respectively. He was a graduate student and postdoctoral research scientist in the Bioelectronic Systems Lab at Columbia University, and he currently works on biosensor platform development at Bialanx in New York City. Matt was previously co-founder and Head of Research at Helixis, a Caltech-based startup company developing low-cost, real-time PCR systems that was acquired by Illumina in 2010. Matt has also held internships with Cavium Networks and The Aerospace Corporation. His current research interests include emerging biosensors, bioelectronic interfaces, microfluidics, massively-parallel sensing, and lab-on-chip technologies for medical monitoring and point-of-care diagnostics.


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