Hi Paul, hi all,

I have recently came across a case in which I have to refine a structure with a 
ligand covalently bound to a Cys of a protein.
I managed to input the geometric restrains for the refinement in phenix, and 
generate a pdb with a LINK line.
However, I would like to real space refine the ligand against a map in coot, 
and I don’t know how to import the restrains for the ligand-Cys covalent bond.
I have already generated and imported to Coot the CIF file for the ligand.
Do I have to use JLigand?

Thanks a lot in advance,
keep up the excellent work,
ciao,
Sebastiano



-- 
Sebastiano Pasqualato, PhD
Crystallography Unit
Department of Experimental Oncology
European Institute of Oncology
IFOM-IEO Campus
via Adamello, 16
20139 - Milano
Italy

tel +39 02 9437 5167
fax +39 02 9437 5990
web http://is.gd/IEOXtalUnit

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