I answer myself if anyone gets into such trouble.

1. I’ve removed xquartz (I’ve used CleanMyMac for that).
2. Reboot
3. I’ve used the script from the xquartz Github 
(https://github.com/XQuartz/XQuartz/blob/XQuartz-2.8.1/pkg/scripts/preinstall 
<https://github.com/XQuartz/XQuartz/blob/XQuartz-2.8.1/pkg/scripts/preinstall>) 
to remove any old traces.
4. Reinstalled xquartz
5. Launch coot in terminal but is was still bugged...
6. Quit terminal
7. Then Xquartz showed a message error about an existing ~/.xinitrc file
8. I moved this file aside, then Xquartz finally launched.
9. Back in terminal, coot launched without any trouble


> Le 29 oct. 2021 à 19:34, Xavier Brazzolotto <xbrazzolo...@gmail.com> a écrit :
> 
> Hi,
> 
> I’ve updated to macOS Monterey (12.0.1) and it seems to have broken by Coot
> 
> Trying to launch from the terminal I get this message
> 
> (coot-crash-catcher.scm:29729): Gtk-WARNING **: cannot open display: 
> /private/tmp/com.apple.launchd.FrfEpN6UFO/org.xquartz:0
> 
> I guess it is related to Xquartz,
> I’ve dowloaded and installed the very last version of Xquartz (2.8.1) but it 
> did not fixed this issue.
> 
> Now xquartz keeps to try to open indefinitely.
> 
> Any hint on how to fix this ?
> 
> Best
> Xavier

Xavier Brazzolotto, PhD
Département de Toxicologie et Risques Chimiques
Institut de Recherche Biomédicale des Armées
BP 73
91223 Brétigny sur Orge
France

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