120px|High resolution computed tomography (HRCT) images of the lower chest in a 16 year-old boy with diffuse panbronchiolitis
Diffuse panbronchiolitis (DPB) is an inflammatory lung disease of unknown cause. It is a severe, progressive form of bronchiolitis, an inflammatory condition of the bronchioles (small air passages in the lungs). DPB causes severe inflammation and nodule-like lesions of terminal bronchioles, chronic sinusitis, and intense coughing with large amounts of sputum production. The disease is believed to occur when there is susceptibility, or a lack of immune system resistance, to DPB-causing bacteria or viruses, caused by several genes that are found predominantly in individuals of East Asian descent. DPB occurs more often in males, and usually begins around age 40. It was recognized as a distinct new disease in the early 1960s, and was formally named "diffuse panbronchiolitis" in 1969. If left untreated, DPB progresses to bronchiectasis, an irreversible lung condition that involves enlargement of the bronchioles, and pooling of mucus in the bronchiolar passages. The eventual result of untreated DPB can lead to respiratory failure and heart problems. Daily treatment of DPB with macrolide antibiotics such as erythromycin eases symptoms and increases survival time, but the disease has no known cure. (more...) Recently featured: Privy Council of the United Kingdom – Art Ross – Compsognathus Archive – By email – More featured articles... Read the rest of this article: <http://en.wikipedia.org/wiki/Diffuse_panbronchiolitis> _______________________________ Today's selected anniversaries: 1759: The British Museum in London, today containing one of the largest and most comprehensive collections in the world, opened to the public in Montagu House, Bloomsbury. <http://en.wikipedia.org/wiki/British_Museum> 1919: A large molasses tank in Boston, Massachusetts, burst and a wave of molasses rushed through the streets , killing 21 people and injuring 150 others. <http://en.wikipedia.org/wiki/Boston_Molasses_Disaster> 1937: Spanish Civil War: Nationalists and Republican both withdrew after suffering heavy losses, ending the Second Battle of the Corunna Road. <http://en.wikipedia.org/wiki/Second_Battle_of_the_Corunna_Road> 1975: Portugal signed the Alvor Agreement with UNITA, the MPLA, and the FNLA, ending the Angolan War of Independence. <http://en.wikipedia.org/wiki/Alvor_Agreement> 1993: Salvatore "The Beast" Riina, one of the most powerful members of the Sicilian Mafia, was arrested after three decades as a fugitive. <http://en.wikipedia.org/wiki/Salvatore_Riina> _____________________________ Wiktionary's word of the day: penny farthing (v): A type of bicycle popular in the 19th century, with the front wheel far larger than the rear one <http://en.wiktionary.org/wiki/penny_farthing> ___________________________ Wikiquote quote of the day: Those whose conduct gives room for talk Are always the first to attack their neighbors. --Molière <http://en.wikiquote.org/wiki/Moli%C3%A8re> _______________________________________________ Wikipedia Daily Article mailing list. To unsubscribe, visit: https://lists.wikimedia.org/mailman/listinfo/daily-article-l Questions or comments? Contact [email protected]
