Hi Klaus, I'm Rich/FlatCap -- Maintainer of NeoMutt. I've just tested the labels and they work for me.
There seem to be a LOT of quotes in your config example.
I've removed a few and everything works as expected:
ifdef edit-label "macro index 'M0' '<edit-label>^U<enter><clear-flag>!' 'Clear
priority (X-Label) of message'"
In this email I've typed out ^U as two separate characters, but in the
config file it's the literal <ctrl-U> character -- kill line.
Please can you try this config and let me know if it works.
Cheers,
Rich
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