Hello,

Has anyone assessed the impact of trimming/filtering reads on assembly
outcome and performance? I would expect very high quality reads to use
less memory and complete assembly a little faster perhaps, but will it
make any impact on the final assembly?

We have run some control with no filtering and the results look great.
However, some recent samples with low read counts and poor qualities
produce no contigs at all. The only thing I can think to do initially
is quality filter and try again. If anyone has compared
filtered/unfiltered assemblies I;d love to know about it.

Jim

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