On 26/04/13 11:37 AM, Marpaud@Gmail wrote:
> Bonjour,
>
> j'ai lu le document concernant en partie les optimal read markers,
> cependant sans la présentation orale correspondante, j'ai un peu de mal à
> bien saisir tout le contenu.

> Translated question: what are optimal read markers ?

Optimal read markers are read markers as described by Daniel Zerbino in his PhD 
thesis.

=> 
http://www.ebi.ac.uk/sites/ebi.ac.uk/files/shared/documents/phdtheses/daniel_zerbino.pdf

=> 
http://www.homolog.us/blogs/2013/01/05/optimal-assembly-for-high-throughput-shotgun-sequencing/



>
> En termes d'algorithme, vais-je devoir éplucher le code de RAY "ligne par
> ligne" ou bien existe-t-il une base plus digeste dont je pourrai me servir
> pour mon travail ?
>

> Translated question: Is it a good idea to read the source code to get a grip 
> on Ray's algorithms ?

No­. You should get acquainted first with de novo genome assembly.

A seminal work in the field include:

* http://www.pnas.org/content/98/17/9748.full

A nice and accessible review:

* http://www.nature.com/nmeth/journal/v6/n11s/abs/nmeth.1376.html


Then, you can read the Ray-related papers:

* http://genomebiology.com/2012/13/12/R122

* http://online.liebertpub.com/doi/abs/10.1089/cmb.2009.0238


> Cordialement.
>


-Sébastien

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