That would be excellent for a GSOC project.

On Tue, Mar 8, 2011 at 8:03 AM, Dhruv Kumar <[email protected]> wrote:

> On Tue, Feb 15, 2011 at 10:43 AM, Shannon Quinn <[email protected]> wrote:
>
> Hi Shannon,
>
>
> >
> > > It would be interesting to see how the current implementation can be
> > > integrated into your Bioinformatics course work, what extensions you
> > > need for this particular domain.
> >
> > I assume your HMM would be for the purpose of protein/nucleic acid
> sequence
> > analysis and alignment. HMMs/MDPs are fairly domain-independent, but this
> > would definitely be an interesting pursuit; I'm a grad student in comp
> bio,
> > and I know a lot of folks who would love to use this.
> >
>
> Yes, I'm interested in applying HMMs for protein sequence analysis, and
> seeing if they can be applied to predict the side chain conformation of
> protein sequences on large data sets using Mahout. The following paper uses
> a HMM in form of a Dynamic Bayesian Network for the same purpose:
>
> http://www.biomedcentral.com/1471-2105/11/306
>
> It will be interesting to extend Mahout's existing HMM code so that it
> could
> be distributed over large clusters. I'm working with a professor here at
> UMass on side chain structure prediction as well this semester and he said
> that we can craft out a nice, tight proposal for this purpose for GSoC.
>
> Dhruv
>
>
>
>
> >
> > On the topic of GSoC, I meant to mention: I'm happy to volunteer my
> > services as a potential mentor for the summer.
> >
> > Shannon
> >
> > Apologies for the brevity, this was sent from my iPhone
>

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