Hi Meikel,
I use InDesign for my wireframes and I am really quite happy with it.
However, I do not use linked Illustrator files. I create all my assets in
InDesign and save them as library items. I have categorized all my assets
and grouped them into 6 libraries which also include certain screen types. I
love using libraries because the assets are labeled and organized well. I
can also see thumbnails of my assets which I can drag and drop onto my
InDesign document as i'm working. If I make any change to my asset, I can
update the library item with the new changes.
A few  limitations of using this method are:
1) If you are working as a team and using the libraries as common assets,
you have to notify other team members to update the library with the changes
made. An InDesign library (.indl) cannot be updated via Version Cue server.
2) The updated asset in the library will not automatically update the asset
previously used in the current document or older documents. So, the updated
asset can only be applied for future use.

Again, this method is only for very rough wireframing and not for
hi-fidelity. However, the wireframes come out very clean and consistent.
When using for presentations, just hide the annotations and call outs (which
you place on a layer) when publishing the PDF. An InDesign document can be
re-purposed for a number of things and is flexible in many ways. I've also
heard that it can also be published as HTML.
Hope this is useful.

-Smitha Ram
Senior Interaction Designer
Thomson Reuters | www.thomsonreuters.com
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