Dear Professors 
Hello, and thanks for any help ahead of time.   
I am a Medical Informatics student at OHSU and right now I am in a  research 
methods class at my institution: Geisinger.   
For My project I wanted to investigate Alert Fatigue, suffering, myself,  
from the condition.  
So far most of what I can document comes from high-risk industries like  
nuclear power, aerospace and the military. There is very little data in the med 
 
informatics literature.  
As I begin the topic though, I can find very little nomenclature defined  
either.  
Is there taxonomy of alerts? And as I start, I really have not found a  
definition of an alert either.  
Is there an official medical informatics definition of ‘alert’?  I propose 
the definition below, would you  please comment on it?  
Alert: “unsolicited 1 signal 2 of  [possible/potential/definite] 3 error 
condition”   
explanation: 
(1) a self posted reminder, like ‘3 days until tax day’ would  not be an 
alert for my purposes.  
(2) Any kind of signal or communication, it could be a  vibrating watch, and 
it does not have to be interruptive or require an action to  continue.  
(3) Many alerts are before the fact, and in medinfo most are  trivial or 
false alarms.  
I would appreciate any help in pointing me to medical informatics  articles 
on experiments in alert fatigue. There is a  lot of data about alerts, and 
about overrides, but not a lot about the human  behavior and what makes an 
alert 
productive and what makes an alert cause other  alerts to fail. I have found 
nothing about how many alerts the mind can take  before it zones out. And even 
the articles that mention how many alerts were  fired in a system and 
overriden, there is nothing I have found yet about how  many alerts per 
encounter, and 
how many alerts per doc per day.   
I have found a few articles  that look at the fatigue effect itself. A 2008 
preprint on overrides vs. number  of alerts and a 2000 article that talks about 
a drag effect of one alert on  overall compliance. These are two of the 
articles that I found that talk about  alert fatigue:

Tiering Drug-Drug Interaction Alerts by Severity Increases  Compliance Rates
http://www.jamia.org/cgi/reprint/M2808v1  


Improving Allergy Alerting in a Computerized Physician Order Entry  System
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=2243998&blobtype=pdf  


There are 3 things that I would like to do in my project:
1:  define an alert, and come up with taxonomy of alerts, there are some 
textbooks  that mention this.
2: present a simple count of alerts by taxonomy and by per  doctor per day. 
So far all I have found is number of alerts in a system over a  month or a 
year, nothing from the doctor point of view or using the doctor in  the 
denominator.
3: start to define the fatigue factor itself. This is based  on a hypothesis 
that the more alerts the more overrides and the less time an  alert is on 
screen. 

A simple approach to the third step would be percent  of overrides morning 
vs. afternoon, Monday vs. Friday as in the sample attached  graph called 
overrides. By pairing Monday morning with Monday afternoon  etcetera, we can 
show 
more significance, and by controlling for rates within  each doctor 
morning/afternoon//Monday-Friday we can get even more significance.  

Any advice on the next step  and other articles would be very welcome.

Thank  you 
Michael Kordek
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