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            LUPUS
           
            Lupus is an autoimmune disease, a type of self-allergy whereby the 
patient's immune system overproduces antibodies which then attack the person's 
own tissues. Lupus is neither infectious nor contagious, and its effect is 
inflammatory. Patients principally suffer extreme fatigue and joint and muscle 
pains. A variety of other symptoms are possible, as well as damage to vital 
organs if the illness has taken a strong hold. Nine out of ten people with 
lupus are female, and whilst it is usually triggered between the ages of 15 and 
50, children can also have the illness.  The incidence of the disease being 
greater in Afro-Caribbean and Asian communities.

            Causes 
            The causes of lupus are not fully understood, although heredity, 
puberty, hormonal activity and change, childbirth, viral infections, sunlight, 
the menopause, trauma or strong medication may play a part in triggering the 
illness. Lupus can affect people of all ages and both sexes. The predominance 
of the illness seen in females is due to the influence of hormonal factors.

            Symptoms 
            Lupus can present in a complex number of ways, even to the extent 
of 'mimicking' other illnesses such as rheumatoid arthritis, multiple sclerosis 
(MS) and myalgic encephalomyelitis (ME). Lupus can be hard to diagnose and the 
condition can be overlooked, sometimes for years, unless the physician is alert 
to its possibility. Many patients differ in symptom patterns, which are taken 
into account with specific blood tests prior to diagnosis.

            A skin problem does not necessarily occur in systemic lupus (SLE) 
but is always present in discoid lupus (DLE), where rashes occurring on the 
face, scalp or neck can be quite severe. Both types arise from a disorder of 
the immune system. DLE can develop into systemic lupus, but does not always do 
so. It is most unusual for the SLE patient to develop DLE. In summary:

            SLE - acute, subacute or chronic skin rashes may occur, mainly on 
the arms and upper body, together with the possibility of a 'butterfly' rash on 
the cheeks.

            DLE - disc-shaped lesions can occur on the face, neck or scalp.

            Lupus is a weighty burden for the patient, being incurable and 
causing physical limitations and pain. Continuous resolve is needed by patients 
and their families to ensure that they are not 'dragged down' by lupus and are 
able to restore and maintain some quality to their lives.

            Treatments
            Both SLE and DLE skin conditions respond to treatment, but may 
recur where the underlying illness flares from time to time. The reasons for 
flare-ups are not always well understood. There is, as yet, no cure. Careful 
monitoring of the illness together with a flexible treatment programme, enables 
the condition to be controlled in the majority of patients. Treatments may 
range from no medication at all in very mild lupus, through NSAIDs 
(non-steroidal anti-inflammatory drugs) and corticosteroids to 
immunosuppressives and even stronger medication, where the illness is more 
serious. As the patient's lupus becomes better managed, the physician will try 
to reduce the volumes and/or levels of medication, eventually to reach the 
lowest possible maintenance level. Patients can learn to reduce the impact of 
the illness by becoming better educated about the condition, by learning to 
'pace' their daily routines, by taking regular rest and by reducing the 
incidence of stress, depression, anger and pain wherever possible. For many 
lupus patients, lifelong medication and care is needed, yet in a smaller 
percentage the illness has been known to recede, particularly after the 
menopause. Physicians now have much greater knowledge of this still-mysterious 
disease and have a wider range of drugs at their disposal, which have made for 
easier control of the individual's own 'brand' of lupus.




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