Could somebody please advise me in the following problem:
I have a summary score consisting of 5 different item, which are
definitely not independent from each other. Each item describes
the severity of a given symptom (medical) on a scale of absent,
mild, moderate or severe. These assessments will be done two
times (baseline and end value) for each individual, who are assigned
to two different treatment groups within each center.
(Repeated assessments in a parallel-group multicenter design using
correlated measures.)
Is there any generalistaion of the Cochran-Mantel-Haenszel methods
for this situation?
One further question is whether somebody could point me to any reference
for a CMH method for symmetry tests (McNemar or Bowker) or in general
for agreement statistics?
Many thanks in advance
Robert N�meth
_____________________________________________
Robert N�meth
Focus Clinical Drug Development GmbH
http://www.focus-cdd.de
Email: [EMAIL PROTECTED]
Tel: +49 (0) 2131 155 315 Fax: +49 (0) 2131 155 378
_____________________________________________
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Focus Clinical Drug Development GmbH, Neuss
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