My response is about regression to the mean generally, which got done 
over a little over a week ago.

It occurred to me recently that you could reduce the 
regression-to-the-mean effect by using the subjects' least-squares 
means to divide them (the subjects) up into quantiles for separate 
analysis (or use the quantiles as a covariate in the model).  That 
would reduce the within-subject error by a factor of 1/root2, if 
there is a single pre and post test, so the RTM effect would be 
reduced accordingly.

See http://trochim.human.cornell.edu/kb/regrmean.htm for an estimate 
of the magnitude of RTM.  It is an amazingly simple 1-r times the 
distance from a pre-test score to the pre-test mean, where r is the 
intraclass correlation coefficient, obtained from a reliability study 
(or, next best thing, obtained by treating the experiment as a 
reliability study).  In other words, the expected drift towards the 
mean is 1-r times the difference between the pre-test score and the 
mean score.  If r=0, expect to regress fully to the mean.  If r=1, 
expect no regression to the mean.  Trochim explains how to take into 
account real shifts in the mean in the post-test.  I hope all this is 
not old hat for this list.

I am grateful to Greg Atkinson at Liverpool John Moores University 
for pointing me to the above website, in case he ever sees this 
message (he's not on this list).  By searching back I see that Gene 
Gallagher <[EMAIL PROTECTED]> also referred to this site in  Re: 
AW: MA MCAS statistical fallacy.   I haven't read the other responses 
on the MCAS statistical fallacy, so I hope I am not repeating anyone 
else's ideas here.

The expression for r is (between^2 - within^2)/between^2, where 
between and within refer to the usual between-subject SD, and within 
is the within-subject error (standard deviation).  With a bit of 
algebra you can show that the RTM effect using the least-squares mean 
of two tests will be (1-r)/2, that is, half the usual value.  If you 
have four tests altogether (e.g., 2 pre, 1 mid, 1 post), then other 
things being equal, the RTM effect will be quarter what it is if you 
use just the pre-test.

I've never done it, but I presume you just subtract off the estimated 
effect of RTM when you want to take account of it.  Putting 
confidence limits on the result will be difficult, I imagine, unless 
you use bootstrapping.

By the way, for those who responded to my query about non-normality 
of residuals, thanks heaps again.  I am in the middle of some 
simulations.  It's taking me a while, because I found that Proc Mixed 
fell over when the variance was zero in a subgroup.  Proc Ttest 
didn't, but it didn't give confidence limits based on unequal 
variances, so I have had to generate those myself from the output 
using version 8 SAS.  I had been using SAS version 6.12 up until now, 
but that didn't generate the required output, nor did it lend itself 
to simulation with Proc Ttest.  Preliminary findings:  that magic 
sample size of 30...

Will



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