Hi

On 26 Sep 2001, Burke Johnson wrote:
> R Pretest   Treatment   Posttest 
> R Pretest    Control       Posttest
> In the social sciences (e.g., see Pedhazur's popular
> regression text), the most popular analysis seems to be to
> run a GLM (this version is often called an ANCOVA), where Y
> is the posttest measure, X1 is the pretest measure, and X2 is
> the treatment variable. Assuming that X1 and X2 do not
> interact, ones' estimate of the treatment effect is given by
> B2 (i.e., the partial regression coefficient for the
> treatment variable which controls for adjusts for pretest
> differences).

> Another traditionally popular analysis for the design given
> above is to compute a new, gain score variable (posttest
> minus pretest) for all cases and then run a GLM (ANOVA) to
> see if the difference between the gains (which is the
> estimate of the treatment effect) is statistically
> significant.

> The third, and somewhat less popular (?) way to analyze the
> above design is to do a mixed ANOVA model (which is also a
> GLM but it is harder to write out), where Y is the posttest,
> X1 is "time" which is a repeated measures variable (e.g.,
> time is 1 for pretest and 2 for posttest for all cases), and
> X2 is the between group, treatment variable. In this case one
> looks for treatment impact by testing the statistical
> significance of the two-way interaction between the time and
> the treatment variables. Usually, you ask if the difference
> between the means at time two is greater than the difference
> at time one (i.e., you hope that the treatment lines will not
> be parallel)

> Results will vary depending on which of these three
> approaches you use, because each approach estimates the
> counterfactual in a slightly different way. I believe it was
> Reichardt and Mark (in Handbook of Applied Social Research
> Methods) that suggested analyzing your data using more than
> one of these three statistical methods.

Methods 2 and 3 are equivalent to one another.  The F for the
difference between change scores will equal the F for the
interaction.  I believe that one way to think of the difference
between methods 1 and 2/3 is that in 2/3 you "regress" t2 on t1
assuming slope=1 and intercept=0 (i.e., the "predicted" score is
the t1 score), whereas in method 1 you estimate the slope and
intercept from the data.  Presumably it would be possible to
simulate the differences between the two analyses as a function
of the magnitude of the difference between means and the
relationship between t1 and t2.  I don't know if anyone has done
that.

Best wishes
Jim

============================================================================
James M. Clark                          (204) 786-9757
Department of Psychology                (204) 774-4134 Fax
University of Winnipeg                  4L05D
Winnipeg, Manitoba  R3B 2E9             [EMAIL PROTECTED]
CANADA                                  http://www.uwinnipeg.ca/~clark
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