"ASK A PHYSICIAN". I went to med school until I was too sick to continue. But I learned enough to never ASK A PHYSICIAN.
On Tue, Feb 11, 2014 at 4:42 PM, John Mikes <jami...@gmail.com> wrote: > Richard: > I salute every step forward, trhey may (or may not) further our cognitive > and operative advancement. This work is in the line of a positive trend - > maybe overestimated in its efficiency - as most are. If they wll be able to > 'evolve' smarter individuals, I place all my blessings on their heads. > > The "brain" is a great mystery, we measure some physical - physiological > data upon it's function and assign them to factors - (also assigned to > brainfubction) furthering bodily and/or mental activity. What do we know > indeed? (Don't ask an agnostic!) > There are no specially marked physical (or physiological) data indicating > the domain of mental activity they belong to. No 'green' mAmps for > emotional, no 'orange' mAmps for scientific, no 'blue' ones for sports, or > 'square' ones for love. > Not even differentiated blood-flow measurements indicate domains they are > said to indicate. Bodily activation is easier to follow, although ASK A > PHYSICIAN... > There is some early try to decipher(?) the different connectivity of > brain-parts into topical differentiation - a good try, but far from > touching the complexity of what we assign to brainfunction - and even that > is a limited model of what may be. > > I confess: I consider the human brain a relay station from source unknown > into human activity and am happy when they find medicament (material, or > treatment) to eliminate (reduce?) pathological consequences. > Of course it is hard to dampen the enthusiasm of the inventor... > > There are so many dimensions etc. we know nothing about and all of them > may influence our 'technology'. > Agnostically yours > John Mikes > > > On Tue, Feb 11, 2014 at 10:18 AM, Richard Ruquist <yann...@gmail.com>wrote: > >> The title of this article is a bit of a reach. >> But these lab results regarding self-organizing >> may be of interest to this list. Richard >> >> >> Human brain artificially created in laboratory >> Published on Mon, Feb 10, 2014 by livia rusu >> >> Post filled in: Genetics, Mind & Brain >> >> >> Human embryonic stem cells can be induced into forming a developing brain >> tissue. The brain development process represents one of the most specific >> processes; during it, neuroepithelium, formed as a flat sheet by the >> nervous system, grows on the exterior layer of the embryo, after which it >> folds in to create a neural tube giving rise to the brain and the spinal >> cord. The process implicates the migration and proliferation of undeveloped >> nerve cells from the brain at one end and the spinal cord at the other. >> >> Human embryonic stem cells spontaneously organize into neuroepithelial >> tissue containing multiple zones after growing for 70 days in culture. Via >> RIKEN. >> >> The discovery made by Yoshiki Sasai, Taisuke KAdoshima and their >> colleagues from RIKEN Center for Developmental Biology consisted in >> treating human embryonic stem (ES) cells by the use of a system with >> signaling molecules inducing the formation of nervous tissue from the outer >> embryonic layer. The thesis of their scientific project was that the cells >> have the capacity of spontaneously organizing into cerebral cortical >> tissues - forming at the front of the developing neural tube. >> >> The previous research of Sasai's team had proven that a new culture >> technique could involve growing ES cells in suspension, showing this way >> that the cells are capable of self-organizing into complex >> three-dimensional structures. The finding served as a methodology >> throughout which pieces of cerebral cortex and embryonic eyes from mouse ES >> cells were grown. Another more recent study has shown that there is a >> complete compatibility with human embryonic stem cells that can also >> organize into embryonic eyes that contain retinal tissue and >> light-sensitive cells. >> >> The last study of Sasai's team showed that the formation of nervous >> tissue from the outer embryonic layer can be induced by treating human ES >> cells to grow using the cell culture system with signaling molecules. This >> was doubled by the finding that the cells spontaneously organize into >> neuroepithelial tissue which folds up immediately after this, to give a >> multilayered cortex. >> >> During the thickening of the front end of the neural tube that happens >> along with the embryonic development at both ends, waves of cells migrate >> outward to mold the layered cerebral cortex as well as other parts of the >> brain. What this study correlates along with this scientific fact is that >> the reason for which the front end of the neural tube's thickening is the >> growth of the glial fiber, spanning the thickness of the tube and guiding >> migrating cells more than due to the accumulation of immature cells within >> the tube, as the scientific community had previously commonly agreed upon. >> >> Another critical difference highlighted by the scientific research >> between the development of the neuronal tube in mice in humans is that in >> humans the inner surface of the neural tube and the intermediate >> neuroepithelial zone underneath it contain distinct populations of neural >> progenitors resembling radial glia. In contrast, the progenitor population >> in mice and rats is not present in the developing of the cortex. Kadoshima >> declared that 'efficient generation of cortical tissues could provide a >> valuable resource of functional neurons and tissues for medical >> applications', suggesting that further research should combine this method >> with disease-specific human induced pluripotent SE cells, while the >> reproduction of complex human disorders is also a possible on the table for >> further experiments. >> >> Read more at http://www.zmescience.com/medicine/genetic/human-brain-stem- >> cells-10022014/#yvrlccr0wdF1c2FO.99 >> >> -- >> You received this message because you are subscribed to the Google Groups >> "Everything List" group. >> To unsubscribe from this group and stop receiving emails from it, send an >> email to everything-list+unsubscr...@googlegroups.com. >> To post to this group, send email to everything-list@googlegroups.com. >> Visit this group at http://groups.google.com/group/everything-list. >> For more options, visit https://groups.google.com/groups/opt_out. >> > > -- > You received this message because you are subscribed to the Google Groups > "Everything List" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to everything-list+unsubscr...@googlegroups.com. > To post to this group, send email to everything-list@googlegroups.com. > Visit this group at http://groups.google.com/group/everything-list. > For more options, visit https://groups.google.com/groups/opt_out. > -- You received this message because you are subscribed to the Google Groups "Everything List" group. 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