I thought this blog post and the ensuing comments were a fascinating 
perspective on the increasing problem of medical science not replicating.

"The Control Group is Out of Control"
http://slatestarcodex.com/2014/04/28/the-control-group-is-out-of-control/
> Trying to set up placebo science would be a logistical nightmare. You’d 
have 
> to find a phenomenon that definitely doesn’t exist, somehow convince a 
whole 
> community of scientists across the world that it does, and fund them to 
study 
> it for a couple of decades without them figuring out the gig.
>
> Luckily we have a natural experiment in terms of parapsychology – the 
study 
> of psychic phenomena – which most reasonable people don’t believe exists 
> but which a community of practicing scientists does and publishes papers 
on 
> all the time.
>
> The results are pretty dismal.

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