Everything that works causes some form of addiction. I myself for example are quite addicted to my glasses and also oxygen. I get severe withdrawal symptoms if I go cold turkey on those things. So talk about addiction or not is pointless. Of interest is side effects and effects, does the drug take all sorts of pain? Just inflammation pain? Neurogenic pain? Phantom pain?
/Henrik Den tis 30 jan. 2024 15:18John Clark <[email protected]> skrev: > By studying a Pakistani family that has a rare mutation that renders them > unable > to feel pain, a small company called Vertex Pharmaceuticals has developed > a drug, that can be taken orally, that has shown significant reduction in > pain in two different drug studies with no clear adverse side effects. The > drug company found that 2 genes, called Nav1.7 and Nav1.8, are needed for > the peripheral nervous system to transmit pain messages to the brain, their > drug works by temporarily blocking the operation of Nav1.8 making it unable > to manufacture the protein needed to transmit such pain messages. In two > different clinical trials, one with 1073 people who were in pain and one > with 1118, the patients reported a significant reduction in pain and they > experienced less nausea and fewer headaches then with opioids, surprisingly > even less than the control patients who received placebos. Because the > drug targets the peripheral nervous system and has no obvious effect on the > brain it is unlikely to cause addiction. Right now the drug is just called > "VX-548" but if it's as good as it sounds and is approved by the FDA it > will be a huge blockbuster and I'm sure they'll think of a catchier name. > > > John K Clark See what's on my new list at Extropolis > <https://groups.google.com/g/extropolis> > pnm > > -- > You received this message because you are subscribed to the Google Groups > "extropolis" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > To view this discussion on the web visit > https://groups.google.com/d/msgid/extropolis/CAJPayv0sJgMg3KXuJwPdnoYVcFsvbV-yhHjai-e8g6p4Lvo%2B_Q%40mail.gmail.com > <https://groups.google.com/d/msgid/extropolis/CAJPayv0sJgMg3KXuJwPdnoYVcFsvbV-yhHjai-e8g6p4Lvo%2B_Q%40mail.gmail.com?utm_medium=email&utm_source=footer> > . > -- You received this message because you are subscribed to the Google Groups "Everything List" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. To view this discussion on the web visit https://groups.google.com/d/msgid/everything-list/CAF0GBnihtoL2ga-QPpZmmPep5UyC%2BDQiYLtgP2ZomtZ5h8-uMQ%40mail.gmail.com.
