Thanks card for posting the article on B12. For decades, as a
vegetarian (mostly -- with a 2-3 year trial exception of fish and
poultry ) and vegan at times, I have been aware of the need to
supplement ones diet with B12. 

I did not know the low absorbsion rate of the almost universally used
form of B12 used in supplements, cobalamin. I bought some of the more
absorbable sub-lingual methyl form yesterday -- its 500 mcg per tab
(hm that phrase has an oddly familiar ring to it). The RNI (Required
Nutritional Intake) is 1.5 mcg. So today, my brain may be functioning
at 300+ times its usual sluggish rate. :)

Actually, I do feel better, more energy, but that might just be from
the coffee I just had from my neighbor the meth manufacturer. :)
Hardly a controlled study.

But I suggest others look into trying the subligual methyl form of B12. 






Here is another article that states similar things as the one you posted.

First an excerpt:

"A deficiency often manifests itself first in the development of
neurological dysfunction that is almost indistinguishable from senile
dementia and Alzheimer's disease. There is little question that many
patients exhibiting symptoms of Alzheimer's actually suffer from a
vitamin B12 deficiency. Their symptoms are totally reversible through
effective supplementation." 

Maybe someone can give MMY daily methyl -- sublingual B12, or shots,
and see if the TMO is suddenly transformed to something like the 70's.




a vitamin B12 deficiency may not manifest itself until after 5 or 6
years of a diet supplying inadequate amounts. Vitamin B12 functions as
a methyl donor and works with folic acid in the synthesis of DNA and
red blood cells and is vitally important in maintaining the health of
the insulation sheath (myelin sheath) that surrounds nerve cells. The
classical vitamin B12 deficiency disease is pernicious anaemia, a
serious disease characterized by large, immature red blood cells. It
is now clear though, that a vitamin B12 deficiency can have serious
consequences long before anaemia is evident. The normal blood level of
vitamin B12 ranges between 200 and 600 picogram/milliliter (148-443
picomol/liter).

A deficiency often manifests itself first in the development of
neurological dysfunction that is almost indistinguishable from senile
dementia and Alzheimer's disease. There is little question that many
patients exhibiting symptoms of Alzheimer's actually suffer from a
vitamin B12 deficiency. Their symptoms are totally reversible through
effective supplementation. A low level of vitamin B12 has also been
associated with asthma, depression, AIDS, multiple sclerosis,
tinnitus, diabetic neuropathy and low sperm counts. Clearly, it is
very important to maintain adequate body stores of this crucial vitamin.

The amount of vitamin B12 actually needed by the body is very small,
probably only about 2 micrograms or 2 millionth of a gram/day.
Unfortunately, vitamin B12 is not absorbed very well so much larger
amounts need to be supplied through the diet or supplementation. The
richest dietary sources of vitamin B12 are liver, especially lamb's
liver, and kidneys. Eggs, cheese and some species of fish also supply
small amounts, but vegetables and fruits are very poor sources.
Several surveys have shown that most strict, long-term vegetarians are
vitamin B12 deficient. Many elderly people are also deficient because
their production of the intrinsic factor needed to absorb the vitamin
from the small intestine decline rapidly with age.

Fortunately, oral supplementation with vitamin B12 is safe, efficient
and inexpensive. Most multi-vitamin pills contain 100-200 microgram of
the cyanocobalamin form of B-12. This must be converted to
methylcobalamin or adenosylcobalamin before it can be used by the
body. The actual absorption of B12 is also a problem with supplements.
Swallowing 500 micrograms of cyanocobalamin can result in absorption
of as little as 1.8 microgram so most multivitamins do not provide an
adequate daily intake. The best approach is to dissolve a sublingual
tablet of methylcobalamin (1000 micrograms) under the tongue every
day. That will be sufficient to maintain adequate body stores.
However, if a deficiency is actually present then 2000 microgram/day
for one month is recommended followed by 1000 microgram/day. Some
physicians still maintain that monthly injections of vitamin B12 is
required to maintain adequate levels in the elderly and in patients
with a diagnosed deficiency. There is however, no scientific evidence
supporting the notion that injections are more effective than
sublingual supplementation. 

http://www.yourhealthbase.com/vitamin_B12.html

and

http://en.wikipedia.org/wiki/Vitamin_B12






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