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The link can be found here:
Example 2
A recombinant feline .omega.-interferon preparation (Trade Name: INTERCAT)
was administered to a one-and-a-half-year-old crossbred male cat which was
observed to have neutropenia due to a feline leukemia virus infection.
On the first day of examination, the cat weighed 2.9 kg and had a body
temperature of 37.0.degree. C., that was low, and had completely lost its
appetite. Vomiting, diarrhea, and dehydration were observed.
It was confirmed that the cat did not have a Parvovirus infectious disease.
Blood test results were as follows: PVC 49%, WBC 3,600, neutrophil 1,476,
lymphocyte 1,440, monocyte 576, eosinophil 108, and thrombocyte 30,000. In the
virus test, an FeLV antigen was detectable, an FIV antibody was not detectable,
and a Parvovirus antigen was not detectable.
The INTERCAT was dissolved in a physiological saline solution and
was subcutaneously injected at a dose of 3 MU/day for four days. The dose was
1.03 MU/kg per cat weight. A transfusion (lactate Ringer's solution and
glucose) was injected by intravenous drip infusion at a dose of 500 ml/day, and
an antibiotic (cephalexin) was intravenously injected at a dose of 100 mg twice
a day.
On the third day, the cat had a body temperature of 39.2.degree. C., had no
appetite, and had continuing diarrhea. Blood test results were as follows: PCV
34%, WBC 20,400, neutrophil 12,700, lymphocyte 3,700, monocyte 1,900, eosinophil
660, and thrombocyte 50,000. On the eighth day, the body temperature had
decreased to 38.8.degree. C. and appetite had slightly improved. The cat weighed
2.6 kg and had slight continuing diarrhea. Blood test results were as follows:
PVC 22%, WBC 62,900, neutrophil 53,000, lymphocyte 2,300, monocyte 6,500,
eosinophil 1,050, and thrombocyte 200,000.
The significant recovery of neutrophils was observed, and alleviation of
fever and improved general condition were observed.
After one month and again after 10 months, no abnormalities
were observed, and thus the therapeutic efficacy of the INTERCAT was
recognized.
Take care,
Glenda
Our FeLV/FIV kitties & other stuff:
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