Example 3
A recombinant feline o-interferon preparation (Trade Name: INTERCAT) was
administered to a 3-year-old crossbred male cat which was observed to have
neutropenia due to a feline leukemia virus infection.
On the first day of examination, the cat had a weight of 4.4 kg and a body
temperature of 41.2.degree. C., and a complete loss of appetite; abscesses and
vomiting were observed.
Blood test results were as follows: PVC 38%, WBC 900, neutrophil 0,
lymphocyte 900, monocyte 0, eosinophil 0, and thrombocyte 30,000. In the virus
test, an FeLV antigen was detectable, an FIV antibody was not detectable, and a
Parvovirus antigen was not detectable.
The INTERCAT was dissolved in a physiological saline solution, and
was subcutaneously injected at a dose of 5 MU/day for seven days. The dose was
1.14 MU/kg per cat weight. A transfusion (lactate Ringer's solution and
glucose) was injected by intravenous drip infusion at a dose of 500 ml/day, and
an antibiotic (cephalexin) was intravenously injected at a dose of 150 mg twice
a day.
On the fifth day, the cat had a body temperature of 40.4.degree. C., had no
appetite, and had continuing diarrhea. Blood test results were as follows: PCV
32%, WBC 10,000, neutrophil 7,300, lymphocyte 2,300, monocyte 200, eosinophil
200, and thrombocyte 150,000.
On the seventh day, the body temperature had decreased to 38.4.degree. C.
and appetite had recovered. Blood test results were as follows: PCV 34%, WBC
16,400, neutrophil 15,000, lymphocyte 1,400, monocyte 0, eosinophil 0, and
thrombocyte 200,000.
Significant recovery of neutrophils was observed, and abatement of
fever and improved general condition were observed.
The FeLV antigen was detectable.
Take care,
Glenda
Our FeLV/FIV kitties & other stuff:
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