OK - let me try to get this thru again... Gloria

I did cut the last part of this message, inculding only the data below... Gloria

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Date: Tue, 11 Mar 2003 19:28:08 -0600
To: [email protected]
From: "Gloria B. Lane" <[EMAIL PROTECTED]>
Subject: Re: Alec Update v. 3.0
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OK - re interferon in the eye, I think there's a bit mention of it at http://www.holisticat.com/eyearch2.html, and other things worth reading about.

Also, there's mention in www.eyevet.com/herpes.html about 'topically applied interferon' to treat herpes:

"Other strategies to assist in the treatment of herpetic keratitis reported in the last few years include topically applied interferon, oral administration of l - lysine and oral administration of cimetidine. Interferon is reported to stimulate the local immunity to viral infection. A 20 to 50 IU/ml solution in artificial tear is administered topically twice daily. Orally administered l - lysine has been reported to inhibit herpesvirus growth by competitive inhibition of the uptake of arginine which is required for viral multiplication. It is given to cats at a dosage of 125 mg twice daily. Cimetidine has been shown to generally stimulate cell mediated immunity. It is given at a dosage of 50 mg once daily. Anecdotal reports suggest that maintenance of cats on one or more of these medications during periods of quiescence, will result in a longer period of time before recrudescence of infection occurs, and that when recrudescence occurs, the infection in milder and of shorter duration."

Ohio State Univ. has this:

"Acute viral respiratory infections are generally self-limiting after 5 to 10 days in most cats. There is no treatment that will eliminate a viral infection. Treatment is mainly supportive and consists of a combination of the following that are most applicable to the patient's manifestations: antibiotics (e.g., amoxicillin) to control secondary bacterial complications, topical ophthalmic antibiotics, nasal decongestants, measures to support nutritional and fluid intake, rest, warmth, and cleaning discharges away from the face. For chlamydia, doxycycline is an effective antibiotic. For severe herpetic corneal ulcers, antiviral agents (e.g., idoxuridine, trifluridine, or vidarabine) can be applied topically in the eyes, but these are expensive."

Vetinfo.com has stuff on Herpes too (http://www.vetinfo.com/cherpes.html#Herpes) - they don't regularly recommend the anti-viral eye drops (but not interferon) because...

"...We tend to hold off on these drops due to the cost, irritating properties and the need for frequent administration of the medications but they probably would help more if we used them earlier. Many of our clients won't continue the drops in their cats due to the cat's reaction to the drops, though. So that discourages us from recommending them quickly. "

Gloria

...


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