Prenisolone and prednisone are interchangeable. Most Vet's (mine is not one) 
believe that prednisolone is better utilized by cats, because one step of the 
metabolization process is eliminated. Prednisone must be processed into 
prednisolone in the liver beofre cats can use it.

"Why are there two versions of this catabolic steroid? First of all, if the 
thought of steroids and cats causes you to picture your cat gaining muscle mass 
and getting ripped, those performance-enhancing drugs are anabolic steroids, 
which build up. Catabolic steroids do the opposite; they break down. A cat’s 
liver processes prednisone, turning it into prednisolone. Prednisolone, then, 
is prescribed for cats with weak or compromised livers." (from

And while my Vet doesn't believe it much matters, she has prescribed 
prednisolone for me  to have on hand, so I can do things my way...

-----Original Message-----
>From: Amani Oakley <>
>Sent: Nov 2, 2017 7:02 PM
>To: "" <>
>Subject: Re: [Felvtalk] Winstrol....
>Hi Bob
>When I was treating Zander, all the vets were using prednisone on cats, so 
>that is what I used on Zander. I don’t agree it is useless. I have used 
>prednisone on other cats, with good result. However, I now understand that 
>prednisolone is a derivative of prednisone and is better and safer for cats. 
>This is my understanding as to why this was changed, but I have heard from 
>vets that the two are interchangeable in terms of dosage, etc.

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